4-tert-ブチルトルエン 化学特性,用途語,生産方法
外観
無色～ほとんど無色透明液体
用途
ポリマー添加剤、防蝕剤原料、香料?溶剤原料、化学工業用中間体
化学的特性
colourless liquid
使用
4-tert-Butyltoluene is used as pharmaceutical intermediate, Solvent for resins, intermediate in organic synthesis. It is an intermediate for the production of the acaricide pyridaben.
製造方法
Synthesis of 4-tert-butyltoluene: Put toluene in the reaction kettle, add catalyst, then add tert-butane chloride, after the reaction, wash with water and layer, and the organic layer is distilled to obtain the product. Alkylation of isobutylene and toluene in the presence of sulfuric acid can also be used to produce 4-tert-butyltoluene.
一般的な説明
Clear colorless liquid with an aromatic gasoline-like odor.
空気と水の反応
Flammable. Insoluble in water.
反応プロフィール
4-tert-Butyltoluene may react with oxidizing materials.
危険性
Toxic by inhalation, ingestion, and skin
absorption. Eye and upper respiratory tract irritant.
健康ハザード
p-tert-Butyl toluene is an irritant
of the mucous membranes, a central nervous
system depressant and may cause cardiovascular
and hematologic disturbances; chronic
exposure in animals causes lung, brain, liver,
and kidney damage.
火災危険
4-tert-Butyltoluene is combustible.
安全性プロファイル
Moderately toxic by
inhalation and ingestion. A skin and human
eye irritant. Human systemic effects by
inhalation: nausea or vomiting, conjunctiva
irritation, unspecified effects on the sense of
taste. Inhalation of vapors causes irritation
of lungs and depression of central nervous
system. Prolonged exposure may result in
damage to liver and kidneys. Flammable
when exposed to heat or flame.
Incompatible with oxidizing materials.
When heated to decomposition it emits
acrid smoke and fumes.
発がん性
p-tert-Butyl toluene was not mutagenic in
a number of bacterial strains in the Ames assay
with or without metabolic activation.
純化方法
A sample containing 5% of the meta-isomer is purified by selective mercuration. Fractional distillation of the solid arylmercuric acetate, after removal from the residual hydrocarbon, gives pure p-tert-butyltoluene [Stock & Brown J Am Chem Soc 81 5615 1959]. [Beilstein 5 H 439, 5 III 1003, 5 IV 1079.]
4-tert-ブチルトルエン 上流と下流の製品情報
原材料
準備製品