3-O-メチルオロボール 化学特性,用途語,生産方法
使用
3''-Methoxy-4'',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2.
3-O-メチルオロボール 上流と下流の製品情報
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