ナビトクラックス 化学特性,用途語,生産方法
効能
抗悪性腫瘍薬, BCL-2阻害薬
化学的特性
Pale Yellow Solid
使用
A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.
作用機序
ABT‐263 exerts its senolytic activity in senescent tumor cells by inhibiting BCL‐XL's interaction with BAX. ABT‐263 is a BH3 mimetic that inhibits anti‐apoptotic BCL‐2 family proteins by impeding their ability to bind pro‐apoptotic proteins, such as BAK and BAX. BCL‐2 and BCL‐XL are the primary targets of ABT‐263 in cancer cells.
ナビトクラックス 上流と下流の製品情報
原材料
準備製品