モノクローナル抗CD31(PECAM-1)抗体-FITC標識 マウス宿主抗体 化学特性,用途語,生産方法
使用
Monoclonal Anti-CD31 (PECAM-1)-FITC antibody has been used in
- DAB based-immunohistochemistry
- direct immunofluorescent staining
- fluorescence-activated cell sorting (FACS)
- flow cytometry
一般的な説明
CD31 is a single chain integral membrane glycoprotein member of the immunoglobulin superfamily of cell adhesion molecules with molecular mass of 130-140kDa. It has six Ig-like loops in the extracellular domain, a trans-membrane domain including a relatively long cytoplasmic domain. It is expressed abundantly on platelets, myeloid cells, B lymphocytes, certain T-lymphocyte cell subsets, bone marrow precursor cells, NK cells and localized to the intracellular junctions in monolayers of cultured endothelial cells.
Biochem/physiol Actions
CD31 is also known as PECAM-1 (Platelet endothelial cell adhesion molecule-1) binds to glycosaminoglycans (GAG). Endothelial CD31 is phosphorylated on tyrosine and serine residues. CD31 is involved in some of the interactive events taking place during cardiovascular development inflammation, thrombosis, wound healing and angiogenesis.
モノクローナル抗CD31(PECAM-1)抗体-FITC標識 マウス宿主抗体 上流と下流の製品情報
原材料
準備製品