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ロクロニウム臭化物

ロクロニウム臭化物 化学構造式
119302-91-9
CAS番号.
119302-91-9
化学名:
ロクロニウム臭化物
别名:
エスラックス;ロクロニウム臭化物;ロクロニウムブロミド;臭化ロクロニウム;1-[17β-(アセチルオキシ)-3α-ヒドロキシ-2β-モルホリノ-5α-アンドロスタン-16β-イル]-1-(2-プロペニル)ピロリジニウム·ブロミド;ロクロニウム HYDROBROMIDE;ロクロニウム 臭化物;ロクロニウム臭化物 (JAN)
英語化学名:
Rocuronium bromide
英語别名:
Eslax;Esmeron;Zemuron;Org-9426;Esmeron:Zemuron;ROCURONIUN BROMIDE;ROCURONIUM BROMIDE;RocuroniuM BroMideAPI;Rocuronium hydrobromide;RocuroniuM BroMide IsoMers
CBNumber:
CB2222507
化学式:
C32H53BrN2O4
分子量:
609.68
MOL File:
119302-91-9.mol

ロクロニウム臭化物 物理性質

融点 :
162-1640C
比旋光度 :
D20 +18.7° (c = 1.03 in CHCl3)
貯蔵温度 :
Room temp
溶解性:
H2O: soluble100mg/mL, clear, light yellow
外見 :
neat
Merck :
14,8246
InChIKey:
OYTJKRAYGYRUJK-FMCCZJBLSA-M
CAS データベース:
119302-91-9(CAS DataBase Reference)

安全性情報

WGK Germany  3

ロクロニウム臭化物 価格 もっと(12)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTR5611 ロクロニウムブロミド
Rocuronium Bromide
119302-91-9 10mg ¥8800 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01LKTR5611 ロクロニウムブロミド
Rocuronium Bromide
119302-91-9 25mg ¥15000 2018-12-26 購入
東京化成工業 R0099 ロクロニウムブロミド >98.0%(T)
Rocuronium Bromide >98.0%(T)
119302-91-9 100mg ¥10600 2018-12-04 購入
Sigma-Aldrich Japan R5155 ロクロニウム 臭化物 ≥98% (perchloric acid titration)
Rocuronium bromide ≥98% (perchloric acid titration)
119302-91-9 50mg ¥21800 2018-12-25 購入
Sigma-Aldrich Japan 1604905 ロクロニウム 臭化物 United States Pharmacopeia (USP) Reference Standard
Rocuronium bromide United States Pharmacopeia (USP) Reference Standard
119302-91-9 250mg ¥71100 2018-12-25 購入

ロクロニウム臭化物 化学特性,用途語,生産方法

効能

骨格筋弛緩薬, 神経筋遮断薬, ムスカリン受容体拮抗薬

商品名

エスラックス (MSD)

説明

Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscular blocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron. k is indicated for use as an adjunct to general anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Rocuroniurn bromide has a significantly more rapid onset than other intermediate acting neuromuscular blockers, comparable to succinylcholine but with a very stable cardiovascular profile and has an improved side effect profile. It has been reported that good to excellent intubation conditions were achieved only one minute after a bolus dose of 600μg/kg of rocuronium bromide. It has a short duration of action, therefore, is useful for rapid sequence intubation without unacceptable delays in the spontaneous recovery of neuromuscular function.

化学的特性

Off-white Solid

Originator

Organon (Netherlands)

使用

Aminosteroid, competitive neuromuscular blocker

使用

A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.

定義

ChEBI: The organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium subs ituents.

brand name

Zemuron (Organon).

生物学の機能

Rocuronium bromide (Zemuron) is a recently approved amino steroid neuromuscular blocking agent. It has a rapid onset of action (1 minute), but its duration of action is intermediate (55 minutes), about that of vecuronium. On rare occasions, it may release histamine and cause cardiac irregularities. Rapacuronium bromide (Raplon) is the most recent neuromuscular blocking agent approved by the United States Food and Drug Administration (FDA). It is an analogue of vecuronium and is thus categorized as an amino steroid. It has a rapid onset of action (1.5 minutes) and a short to intermediate duration of action (20 minutes).This makes it a suitable alternative to mivacurium or succinylcholine for short procedures. It is eliminated mainly by the liver.Adverse effects are dose dependent; they include tachycardia, hypotension, and bronchospasm. These effects may be related to the ability of the drug to release a small amount of histamine.

ロクロニウム臭化物 上流と下流の製品情報

原材料

準備製品


ロクロニウム臭化物 生産企業

Global( 246)Suppliers
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Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19919 60
Henan DaKen Chemical CO.,LTD.
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Henan Tianfu Chemical Co.,Ltd.
0371-55170693
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ATK CHEMICAL COMPANY LIMITED
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119302-91-9(ロクロニウム臭化物)キーワード:


  • 119302-91-9
  • Eslax
  • Rocuronium Bromide (250 mg)
  • RocuroniuM BroMide IsoMers
  • 1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-14-(acetyloxy)-5-hydroxy-2,15-diMethyl-4-(Morpholin-4-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-iuM
  • 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(4-Morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidiniuM BroMide
  • 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-diMethyl-2-Morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-iuM broMide
  • ROCURONIUM BROMIDE
  • [3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enyl-2,3,4,5-tetrahydropyrrol-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl] acetate bromide
  • ROCURONIUN BROMIDE
  • 1-[(2b,3a,5a,16b,17b)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide
  • RocuroniuM BroMideAPI
  • Pyrrolidinium, 1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
  • Rocuronium hydrobromide
  • 1-[17β-(Acetyloxy)-3α-hydroxy-2β-(morpholin-4-yl)-5α-androstan-16β-yl]-1-(prop-2-enyl)pyrrolidinium bromide
  • Esmeron
  • Org-9426
  • Zemuron
  • Rocuronium Bromide/1-[17B-(acetyloxy)-3a-hydroxy2B-(4-morpholinyl)-5a-androstan-16B-yl]-1-(2-propenyl)pyrrolidinium bromide
  • 1-[17B-(acetyloxy)-3a-hydroxy2B-(4-morpholinyl)-5a -androstan-16B-yl]-1-(2-propenyl)pyrrolidinium bromide
  • 1-[17B-(acetyloxy)-3a-hydroxy-2B-(4-morpholinyl)-
  • 1-[(2,3a,5a,16,17)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide
  • 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)andrcstan-16-y1]-1-propenylpyrrolidinium bromide
  • Esmeron:Zemuron
  • エスラックス
  • ロクロニウム臭化物
  • ロクロニウムブロミド
  • 臭化ロクロニウム
  • 1-[17β-(アセチルオキシ)-3α-ヒドロキシ-2β-モルホリノ-5α-アンドロスタン-16β-イル]-1-(2-プロペニル)ピロリジニウム·ブロミド
  • ロクロニウム HYDROBROMIDE
  • ロクロニウム 臭化物
  • ロクロニウム臭化物 (JAN)
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