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N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide

化学構造式
1190378-57-4
CAS番号.
1190378-57-4
化学名:
别名:
英語名:
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
英語别名:
CS-2840;MRT68921;MRT67307;MRT67307 HCl;MRT67307 (free base);MRT67307 hydrochloride;MRT67307 HCl(free-base);IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem;N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide;Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-
CBNumber:
CB22547040
化学式:
C26H36N6O2
分子量:
464.6
MOL File:
1190378-57-4.mol

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide 物理性質

比重(密度) :
1.270
貯蔵温度 :
Keep in dark place,Sealed in dry,2-8°C
溶解性:
H2O: 可溶15mg/mL、透明
外見 :
粉
酸解離定数(Pka):
15.94±0.20(Predicted)
色:
白から薄茶色
InChIKey:
UKBGBACORPRCGG-UHFFFAOYSA-N

安全性情報

WGK Germany  3

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan SML0702 ≥98% (HPLC)
MRT67307 hydrochloride ≥98% (HPLC)		 1190378-57-4 5mg ￥26200 2024-03-01 購入
Sigma-Aldrich Japan SML0702 ≥98% (HPLC)
MRT67307 hydrochloride ≥98% (HPLC)		 1190378-57-4 25mg ￥79100 2024-03-01 購入

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide 化学特性,用途語,生産方法

使用

MRT67307 hydrochloride has been used to study its effect on LPS (lipopolysaccharide) -induced lysosome tubulation.

Biochem/physiol Actions

MRT67307 is an amino-pyrimidine derivative and has an IC50 value of 19. It is known to induce TLR (toll like receptor) mediated anti inflammatory cytokine generation. Also, MRT67307 prevents the secretion of cytokines associated with proinflammation.

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide 上流と下流の製品情報

原材料

準備製品

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide 生産企業

Global( 82)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Shandong chuangyingchemical Co., Ltd. 		18853181302
sale@chuangyingchem.com CHINA 5909 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 47465 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490
 info@gihichemicals.com China 49999 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33349 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58

  スペクトルデータ(1HNMR)

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide(1190378-57-4)1HNMR
  • 1190378-57-4
  • MRT67307
  • MRT67307 hydrochloride
  • N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide hydrochloride
  • MRT68921
  • N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
  • MRT67307 (free base)
  • IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem
  • MRT67307 HCl
  • CS-2840
  • Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-
  • MRT67307 HCl(free-base)
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