ナイシン

ナイシン 化学構造式
1414-45-5
CAS番号.
1414-45-5
化学名:
ナイシン
别名:
ナイシン;ナイシン ラクチス乳酸菌由来;ニシン;L-Ile-3-メチルDha-D-Cys(1)-L-Ile-ΔAla-L-Leu-L-Ala(1)-3-メチル-D-Ala(2)-L-Pro-Gly-L-Cys(2)-L-Lys-3-メチル-D-Ala(3)-Gly-L-Ala-L-Leu-L-Met-Gly-L-Cys(3)-L-Asn-L-Met-L-Lys-3-メチル-D-Ala(4)-L-Ala-3-メチル-D-Ala(5)-L-Cys(4)-L-His-L-Cys(5)-L-Ser-L-Ile-L-His-L-Val-ΔAla-L-Lys-OH;ナイシンA
英語名:
Nisin
英語别名:
NisinCAS:1414-45-5;NISIN;MISIN;Ambicin N;nsc-112903;Aids032124;Nisin (>Aids-032124;Nisin (8CI);Nisin Powder
CBNumber:
CB2257501
化学式:
C143H230N42O37S7
分子量:
3354.07
MOL File:
1414-45-5.mol

ナイシン 物理性質

沸点 :
2967℃
比重(密度) :
1.02 g/mL
闪点 :
>110°(230°F)
貯蔵温度 :
-20°C
溶解性:
insoluble in H2O; insoluble in EtOH; ≥5.63 mg/mL in DMSO with gentle warming and ultrasonic
外見 :
解決
水溶解度 :
水に溶ける
Merck :
13,6592
InChIKey:
NVNLLIYOARQCIX-QSXKFZIVNA-N
CAS データベース:
1414-45-5

安全性情報

主な危険性  Xn
Rフレーズ  22-36/37/38
Sフレーズ  22-24/25-36-26
WGK Germany  3
RTECS 番号 QU3340000
10
毒性 mouse,LD50,intravenous,100mg/kg (100mg/kg),"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(2), Pg. 228, 1980.

ナイシン 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01MPB02155839 ナイシン
Nisin
1414-45-5 5g ¥25800 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01MPB02155839 ナイシン
Nisin
1414-45-5 25g ¥71000 2024-03-01 購入
Sigma-Aldrich Japan N5764 ナイシン ラクチス乳酸菌由来 2.5% (balance sodium chloride)
Nisin from Lactococcus lactis 2.5% (balance sodium chloride)
1414-45-5 1g ¥13800 2024-03-01 購入
Sigma-Aldrich Japan N5764 ナイシン ラクチス乳酸菌由来 2.5% (balance sodium chloride)
Nisin from Lactococcus lactis 2.5% (balance sodium chloride)
1414-45-5 5g ¥33900 2024-03-01 購入
Sigma-Aldrich Japan SBR00021 (20,000-40,000 IU/mL in 0.02N HCl)
Nisin Ready Made Solution (20,000-40,000 IU/mL in 0.02N HCl)
1414-45-5 1ml ¥23100 2024-03-01 購入

ナイシン MSDS


Nisin

ナイシン 化学特性,用途語,生産方法

用途

保存料等

化学的特性

Crystals from ethanol. Derived from Streptococcus lactis Lancefield Group N.

使用

Nisin is an antimicrobial agent derived from pure culture fermenta- tions of certain strains of streptococcus lactis lancefield group n. nisin preparation contains nisin, a group of related peptides with antibiotic activity. it is used to inhibit the outgrowth of clostridium botulinum spores and toxin formation in pasteurized cheese spreads and pasteurized process cheese spreads; pasteurized cheese spread with fruits, vegetables, or meats; and pasteurized process cheese spread with fruits, vegetables, or meats.

定義

ChEBI: A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium L ctococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life.

副作用

Although Nisin E234 generally regarded as a very safe and effective supplement, there can be some minor side effects. Possible side effects: pruritus, nausea, and flushing. Other side effects include: pruritus, skin rash, and vomiting.

純化方法

This polypeptide from S. lactis is purified by crystallisation from 80% (v/v) EtOH and by countercurrent distribution. The synthetic polypeptide antibiotic can also be purified by preparative HPLC and assayed by HPLC on a Nucleosil 3007C18 (6 x 250mm) column using a MeCN—0.01M HCl gradient (30-50%), at 2%/minute, and flow rate of 1.5mL/minute to give a retention time of 8.1 minutes; or MeCN—0.3M guanidine-HCl gradient (30-50%), at 2%/minute, and flow rate of 1.5ml/minute to give a retention time of 10.9minutes. FAB-MS gave the pseudomolecular ion m/z at 3352.7 (M + H)+. It is soluble in dilute acid and is stable even on boiling. [Berridge et al. Biochem J 52 529 1952, synthesis by Fukase et al. Tetrahedron Lett 29 795 1988.]

ナイシン 上流と下流の製品情報

原材料

準備製品


ナイシン 生産企業

Global( 342)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
+86-0086-025-69916489 +86-18852044786
tongyuansales@vip.sina.com China 323 58
Hengshui Haoye Chemical Co.,Ltd.
+86-2102300 +86-18632882519
hy@chemcoms.com China 256 58
BOC Sciences
+16314854226
inquiry@bocsci.com United States 19743 58
Across Biotech Jinan Co LTD
+8613031735486
frank@acrossbiotech.com China 105 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12456 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109
xinshengkeji@xsmaterial.com China 1100 58
Shanghai Affida new material science and technology center
+undefined15081010295
2691956269@qq.com China 359 58
airuikechemical co., ltd.
+undefined86-15315557071
sales02@airuikechemical.com China 994 58
Hunan aslsen technology co.,ltd
+8619313031929
aslsd@aslsen.com China 128 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
sarah@tnjone.com China 893 58

1414-45-5(ナイシン)キーワード:


  • 1414-45-5
  • L-Isoleucyl-(Z)-2,3-didehydro-2-aminobutanoyl-D-cysteinyl-L-isoleucyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-threo-3-mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoylglycyl-L-alanyl-L-leucyl-L-methionylglycyl-L-cysteinyl-L-asparaginyl-L-methionyl-L-lysyl-threo-3-mercapto-D-2-aminobutanoyl-L-alanyl-threo-3-mercapto-D-2-aminobutanoyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-seryl-L-isoleucyl-L-histidyl-L-valyl-2,3-didehydroalanyl-L-lysine cyclic (3->7),(8->11),(13->19),(23->26),(25->28)-pentakis(sulfide)
  • NISIN
  • nsc-112903
  • Streptococcus element (element)
  • Nisin from Lactococcus lactis Vetec(TM) reagent grade, 2.5% (balance sodium chloride and denatured milk solids)
  • Nisin from Lactococcus lactis
  • NISINSTREPTOCOCCUS LACTIS
  • nisin from streptococcus lactis
  • NisinC143H228N42O37S7
  • nisin from lactococcus lactis
  • NISINSTREPTOCOCCUS LACTIS: 2.5% NISIN, 75% DENATURED MILK SOLIDS
  • Ambicin N
  • Aids032124
  • Aids-032124
  • MISIN
  • Nisin Lactococcus lactis
  • Lactic acid Streptococcus
  • Nisin (>900 IU/mg, contains min. 50% NaCl)
  • Food/Beverage/Cosmetics Natural Preservative Nisin/nisin e234
  • Nisin Ready Made Solution
  • Nisin Powder
  • Nisin Z, ≥900 IU/mg
  • Nisin (>
  • 900 IU/mg, contains min. 50% NaCl)
  • NISIN(1414-45-5)
  • Nisin USP/EP/BP
  • Food Ingredient Preservative Nisin CAS No.?1414-45-5?Crystal Powder
  • Good Quality Nisin Food Gradewith ISO FDA Halal Kosher
  • Nisin AQ: What is Nisin A Q: What is the CAS Number of Nisin A
  • (20,000-40,000 IU/mL in 0.02N HCl)
  • ナイシン
  • ナイシン ラクチス乳酸菌由来
  • ニシン
  • L-Ile-3-メチルDha-D-Cys(1)-L-Ile-ΔAla-L-Leu-L-Ala(1)-3-メチル-D-Ala(2)-L-Pro-Gly-L-Cys(2)-L-Lys-3-メチル-D-Ala(3)-Gly-L-Ala-L-Leu-L-Met-Gly-L-Cys(3)-L-Asn-L-Met-L-Lys-3-メチル-D-Ala(4)-L-Ala-3-メチル-D-Ala(5)-L-Cys(4)-L-His-L-Cys(5)-L-Ser-L-Ile-L-His-L-Val-ΔAla-L-Lys-OH
  • ナイシンA
Copyright 2017 © ChemicalBook. All rights reserved