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(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide

化学構造式
1417997-93-3
CAS番号.
1417997-93-3
化学名:
别名:
英語名:
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
英語别名:
22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
CBNumber:
CB23373154
化学式:
C22H19NO3
分子量:
345.39
MOL File:
1417997-93-3.mol

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 物理性質

比重(密度) :
1?+-.0.06 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMSO: soluble
外見 :
A solid
酸解離定数(Pka):
8.76±0.23(Predicted)

安全性情報

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 化学特性,用途語,生産方法

説明

HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).

使用

(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 上流と下流の製品情報

原材料

2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl)-, ethyl ester, (E)- 7-メトキシクマリン

準備製品

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide 生産企業

Global( 58)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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Career Henan Chemica Co 		+86-0371-86658258 15093356674;
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HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
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InvivoChem 		+1-708-310-1919 +1-13798911105
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Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2923 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4121 55

  スペクトルデータ(1HNMR)

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide(1417997-93-3)1HNMR

1417997-93-3()キーワード:

N-ベンジル-N-メチル-1-(4-(トリフルオロメチル)ベンジル)ピペリジン-3-カルボキサミド
  • 1417997-93-3
  • INVIVO-7933
  • (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
  • (2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
  • 2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)-
  • HDAC8-IN-22d
  • HDAC8 inhibitor 22d
  • CS-2693
  • HDAC8 inhibitor 1
  • MDK-7933
  • HDAC8-IN-1 ,MDK7933
  • (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
  • 22d
  • HDAC8-IN-1
  • HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
  • HDAC8-IN-1(22d)
  • (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
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