クロリンE6

クロリンE6 価格 もっと(3)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01COBQC-6466	クロリンe6 Chlorin e6	19660-77-6	100mg	￥60000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBQC-6466	クロリンe6 Chlorin e6	19660-77-6	250mg	￥120000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBQC-6466	クロリンe6 Chlorin e6	19660-77-6	1g	￥290000	2024-03-01	購入

クロリンE6 化学特性,用途語,生産方法

説明

Chlorin E6 is a natural molecule and a promising photosensitizer. Chlorin E6 is isolated from renewable natural sources. Chlorin E6 is an attractive photodynamic therapy (PDT) drug candidate because of (1) its high absorption in the red spectral region, and (2) its low cost to make compared to other porphyrin-based PDT drugs. Chlorin E6 exhibits advantageous photophysical properties for PDT such as having long lifetimes in their photoexcited triplet states and high molar absorption in the red region of the visible spectrum. Moreover, a 664-nm laser light can penetrate tissue deeper that the 630-nm laser light used for other PDT drugs. Chlorin E6 is an important starting material for making PDT drug Talaporfin sodium (mono-L-aspartyl chlorin e6 or NPe6).
PDT is currently being used as an alternative therapeutic modality for a variety of malignant tumors. Studies have examined antitumor activity of Ce6-induced PDT (Ce6-PDT) both in vitro and in vivo using a rat tumor models. In one study three-week-old male Sprague-Dawley (SD) rats were inoculated s.c. on the right flank with 5x106 RK3E-ras cells. The animals were administered i.v. with Ce6 (10 mg/kg) and 24 h later, PDT was performed using a laser diode at a light dose of 100 J/cm2. Ce6-PDT generated reactive oxygen species and led to significant growth inhibition in RK3E-ras cell. In addition, Ce6-PDT induced apoptosis through the activation of caspase-3 and its downstream target, PARP cleavage. The protein level of anti-apoptotic bcl-2 was also reduced by Ce6-PDT in RK3E-ras cells. In in vivo experiments, application of Ce6- PDT led to a significant reduction of tumor size. PCNA immunostaining and TUNEL assay revealed that Ce6-PDT inhibited tumor cell proliferation and increased apoptosis. (source: Oncology Reports, 2009, 22(5). 1085-1091.)

使用

Chlorin E6 is a photosensitizer.The conjugates of gold nanorods and chlorin e6 enhance the fluorescence detection and photodynamic therapy (PDT) of cancers.

クロリンE6 上流と下流の製品情報

原材料

準備製品

クロリンE6 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	nutrabiotech@outlook.com	China	300	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9350	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
CHEMSOON CO.,LTD.	+8613761723174	sales01@chemsoon.com	China	1211	58

19660-77-6(クロリンE6)キーワード:

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• 19660-77-6
• CHLORIN E6
• PHYTOCHLORIN
• 12,17-tetramethyl-3-dihydro-(2s-trans)-thyl-7
• 21h,23h-porphine-2-propanoicacid,18-carboxy-20-(carboxymethyl)-8-ethenyl-13-e
• (2S-trans)-18-carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionic acid
• 21H,23H-Porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7S,8S)-
• (2S-trans)-18-Crboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionic acid
• CHLORIN E6 Phytochlorin
• 3(S),7,12,17-Tetramethyl-13-ethyl-8-ethenyl-2,3-dihydro-18-carboxy-20-(carboxymethyl)-21H,23H-porphine-2(S)-propanoic acid
• Aids006251
• Aids-006251
• Chlorine a6
• Photochlorine
• orin E6
• (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid
• Chlorin E6,>90%
• Chlorophyll Impurity 11
• CHLORIN E6 TRISODIUM SALT
• Chlorine e6
• Photolon
• (7S,8S)-7-(2-Carboxyethyl)-5-(carboxymethyl)-18-ethyl-2,8,12,17-tetramethyl-13-vinyl-7H,8H-porphyrin-3-carboxylic acid
• (7S,8S)-3-Carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphine-7-propionic Acid
• HLORIN E6
• クロリンE6
• (2S)-18-カルボキシ-20-(カルボキシメチル)-8-エテニル-13-エチル-2,3-ジヒドロ-3α,7,12,17-テトラメチル-21H,23H-ポルフィリン-2β-プロパン酸
• (2S,3S)-18-カルボキシ-20-(カルボキシメチル)-8-エテニル-13-エチル-2,3-ジヒドロ-3,7,12,17-テトラメチル-21H,23H-ポルフィリン-2-プロパン酸
• 3-[(21S,22S)-11,16-ジエチル-12,17,21,26-テトラメチル-4-オキソ-7,23,24,25-テトラアザヘキサシクロ[18.2.1.15,8.110,13.115,18.02,6]ヘキサコサ-1,5,8(26),9,11,13(25),14,16,18,20(23)-デカエン-22-イル]プロパン酸
• フィトクロリン
• (2S)-3α,7,12,17-テトラメチル-8-ビニル-13-エチル-18-(ヒドロキシカルボニル)-20-(2-オキソ-2-ヒドロキシエチル)-2,3-ジヒドロ-21H,23H-ポルフィリン-2β-プロパン酸
• (19S,20S)-20-(2-カルボキシエチル)-2-(カルボキシメチル)-14-エテニル-9-エチル-5,10,15,19-テトラメチル-21,22,23,24-テトラアザペンタシクロ[16.2.1.13,6.18,11.113,16]テトラコサ-1,3(24),4,6,8,10,12,14,16(22),17-デカエン-4-カルボン酸
• フィトクロリンe6
• クロリンa6