バラシクロビル
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
|
| 注意書き |
| P264 |
取扱い後は皮膚をよく洗うこと。 |
| P264 |
取扱い後は手や顔をよく洗うこと。 |
| P270 |
この製品を使用する時に、飲食または喫煙をしないこ と。 |
| P301+P312 |
飲み込んだ場合：気分が悪い時は医師に連絡する こと。 |
| P330 |
口をすすぐこと。 |
| P501 |
内容物/容器を．．．に廃棄すること。 |
|
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQJ-2996 |
Valaciclovir |
124832-26-4 |
100mg |
￥585000 |
2024-03-01 |
購入 |
バラシクロビル 化学特性,用途語,生産方法
効能
抗ウイルス薬, DNAポリメラーゼ阻害薬
化学的特性
White Solid
使用
The L-Valine ester prodrug of Acyclovir.
Valacyclovir (Valtrex) is the 1-valine ester (prodrug) of acyclovir that exhibits no activity until hydrolyzed in the intestinal wall or liver to acyclovir and its active metabolite. Its modified structure allows increased intestinal absorption and concomitant higher plasma levels of acyclovir. It demonstrates activity against HSV types 1 and 2, varicella-zoster virus, and cytomegalovirus. It exerts its effects by interfering with DNA synthesis through phosphorylation by viral thymidine kinase and subsequent inhibition of viral DNA polymerase, thereby inhibiting viral replication. Valtrex is indicated for the treatment of acute herpes zoster and recurrent genital herpes in immunocompetent adults. The most common side effects are headache, nausea, and vomiting.
適応症
Valacyclovir (Valtrex) is the 1-valine ester (prodrug) of acyclovir that exhibits
no activity until hydrolyzed in the intestinal wall or liver to acyclovir and its
active metabolite. Its modified structure allows increased intestinal absorption
and concomitant higher plasma levels of acyclovir. It demonstrates activity
against HSV types 1 and 2, varicella-zoster virus, and cytomegalovirus.
It exerts its effects by interfering with DNA synthesis through phosphorylation
by viral thymidine kinase and subsequent inhibition of viral DNA
polymerase, thereby inhibiting viral replication. Valtrex is indicated for the
treatment of acute herpes zoster and recurrent genital herpes in immunocompetent
adults. The most common side effects are headache, nausea, and
vomiting.
Valacyclovir is the only antiviral agent approved for herpes labialis,
for a 3-day course in the episodic treatment of recurrent genital herpes (2).
Valacyclovir is indicated for recurrent genital herpes and is administered at
500 mg twice daily for 3 days at the onset of prodromal symptoms or at the first
sign of infection.
薬理学
Valacyclovir (Valtrex), a valine ester prodrug of acyclovir, has
a bioavailability three to five times that of acyclovir. This is due to its improved
gastrointestinal absorption compared to acyclovir. Valacyclovir is rapidly and
almost completely converted to acyclovir after oral administration, with levels
comparable to those of intravenous acyclovir. This allows for twice-daily dosing,
which may improve compliance and ultimate clinical efficacy. It is more costly
than acyclovir.
バラシクロビル 上流と下流の製品情報
原材料
準備製品
バラシクロビル 生産企業
Global( 216)Suppliers
124832-26-4(バラシクロビル)キーワード:
- 124832-26-4
- Valaciclovir & Valaciclovir Hydrochloride
- Valacyclovir-d4
- L-VALINE 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9YL)METHOXY]ETHYL ESTER
- L-VALINE 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9YL)METHOXY]ETHYL ESTER, HYDROCHLORIDE SALT
- l-valine 2-(guanin-9-ylmethoxy)ethyl ester
- VALACICLOVIR
- VALACV
- VALACICLOVIR 99+%
- ValaciclovirBase
- Valaciclovir Hydrochloride 124832-27-5 / Base
- 256U87
- L-Valine ester with 9-[(2-hydroxyethoxy)methyl]guanine
- L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester (9CI)
- 100MG/1G/1KG
- Valcivir
- Valacyclovir Hydrochloride Hydrate (L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride hydrate
- Valaciclovir USP/EP/BP
- ValacyclovirQ: What is
Valacyclovir Q: What is the CAS Number of
Valacyclovir Q: What is the storage condition of
Valacyclovir Q: What are the applications of
Valacyclovir
- VALACICLOVIR HCL
- VALACICLOVIR HYDROCHLORIDE
- VALACYCLOVIR
- バラシクロビル
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