グリシジルフェニルエーテル 化学特性,用途語,生産方法
外観
無色〜わずかにうすい黄色, 澄明の液体
溶解性
エタノール及びアセトンに極めて溶けやすく、水にやや溶けにくい。
用途
界面活性剤、農薬安定剤、エポキシ樹脂希釈剤、エポキシ樹脂?アルキッド樹脂の反応性希釈剤、繊維の改質剤、合成樹脂?農薬の補助剤
用途
有機合成原料。
主な用途／役割
エポキシ樹脂接着剤の希釈剤として使用される。
使用上の注意
かぶれやすい性質がある。
化学的特性
Phenyl glycidyl ether, also known as glycidyl phenyl ether or PGE, is a clear liquid with a sweet odor that is considered unpleasant. It is soluble in ether and benzene, but insoluble in water. It has the ability to volatilize with water vapor. It is used in the production of epoxy resins, as a chemical intermediate, and as a stabilizer.
使用
Phenyl glycidyl ether (PGE) is utilized in organic syntheses as an intermediate. As a reactive diluent, PGE is incorporated into uncured epoxy resins to lower viscosity, thereby facilitating casting, adhesives, and laminating applications.
調製方法
PGE is synthesized by condensation of phenol with epichlorohydrin,
with subsequent dehydrochlorination with caustic
to form the epoxy ring.
一般的な説明
Colorless liquid.
空気と水の反応
Ethers tend to form unstable peroxides when exposed to oxygen. Ethyl, isobutyl, ethyl tert-butyl, and ethyl tert-pentyl ether are particularly hazardous in this respect. Ether peroxides can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Slightly soluble in water.
反応プロフィール
Glycidyl phenyl ether, an ether, can act as a base. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
健康ハザード
PGE is a toxic compound exhibiting moderate irritant action and carcinogenicity inanimals. Application of 0.25 mg resulted insevere eye irritation in rabbits, while 500 mgcaused moderate skin irritation over a periodof 24 hours. Prolonged or repeated contactcan cause moderate irritation and skin sensitization in humans.
The symptoms of its toxicity in animalswere depression of the central nervous system and paralysis of the respiratory tract.Prolonged exposure caused changes in thekidney, liver, thymus, and testes, and lossof hair in rats. The toxicity of this compound in humans is low and the health hazardcan arise primarily from its skin-sensitizationaction.
LD50 value, oral (mice): 1400 mg/kg
DGE showed carcinogenicity in rats, causingnasal cancer.
火災危険
Glycidyl phenyl ether is probably combustible.
接触アレルゲン
This monoglycidyl derivative is a reactive diluent in
epoxy resins Bisphenol A type. It is a component of
epoxy paints, epoxy glues, and epoxy resins.
Sensitization has been observed in many professions,
such as in construction workers, marble workers,
ceramic workers, and shoemakers.
安全性プロファイル
Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion, skin contact, and subcutaneous routes. A severe eye and skin irritant. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used as a chemical intermediate. See also ETHERS
職業ばく露
PGE is used to increase storage time and stability of halogenated compounds; as a reactive diluent in uncured epoxy resins to reduce the viscosity of the uncured system for ease in casting; adhesive, and laminating applications. NIOSH once estimated that 8000 workers are potentially exposed to PGE.
発がん性
Chronic exposure of rats to 1 or 12ppm
6 hours/day, 5 days/week for 2 years caused an
increased incidence of rhinitis, squamous metaplasia,
and epidermal carcinomas of the nasal
cavity.4 The IARC has determined that there is
sufficient evidence for the carcinogenicity of
PGE in animals and that it is possibly carcinogenic
to humans.
輸送方法
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
不和合性
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, amines, and curing agents. PGE can presumably form explosive peroxides
廃棄物の処理
Concentrated waste containing no peroxides-discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxidesperforation of a container of the waste from a safe distance followed by open burning.
グリシジルフェニルエーテル 上流と下流の製品情報
原材料
準備製品