ホスホジエステラーゼ 3′,5′-環状ヌクレオチド 活性化因子欠損 ウシ心臓由来 化学特性,用途語,生産方法
用途
製造用剤
使用
For use in calmodulin (P 0270) assay. Activity is reduced to <50% without calmodulin present.
一般的な説明
Phosphodiesterase (PDE1) exists in two isoforms -PDE1A2 and PDE1B1. The enzyme has a role in the complex interaction between cyclic nucleotides and Ca
2+ second-messenger systems.
臨床応用
Phosphodiesterase-3 (PDE3) is an enzyme responsible for degradation of cAMP to AMP in platelets
and blood vessels. Selective cAMP PDE3 inhibitors, such as dipyridamole and cilostazol , inhibit the degradation of cAMP, thereby increasing cellular concentration of cAMP and
leading to inhibition of platelet aggregation and vasodilation.
ホスホジエステラーゼ 3′,5′-環状ヌクレオチド 活性化因子欠損 ウシ心臓由来 上流と下流の製品情報
原材料
準備製品