(+/-)-BAY K 8644 化学特性,用途語,生産方法
一般的な説明
Synthetic dihydropyridine derivative that acts as an active Ca
2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca
2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca
2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca
2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.
Biochem/physiol Actions
Primary TargetL-type Ca2+ channel
(+/-)-BAY K 8644 上流と下流の製品情報
原材料
準備製品