プロパセタモール 化学特性,用途語,生産方法
効能
鎮痛薬, 解熱薬
説明
Propacetamol is the prodrug of paracetamol (acetaminophen),
used for intravenous administration. It
results from eombination of paracetamol and diethylglycine.
Causes contact dermatitis and airborne dermatitis
in nurses. Allergenic properties are due to the
N,N' -diethylglycine moiety, and not to the paracetamol
moiety.
使用
Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.
接触アレルゲン
Propacetamol is a prodrug of paracetamol (acetaminophen)
used for intravenous administration. It results
from the combination of paracetamol and diethylglycine.
It caused contact (hand and airborne) dermatitis in
nurses and acute systemic dermatitis (pompholyx and
nummular dermatitis, generalized eczema, urticaria-like
eruption) in nurses who had became sick and received
intravenous propacetamol. Allergenic properties are due
to the N,N-diethylglycine moiety, and not to the paracetamol
moiety. Propacetamol is now substituted by a
solution of paracetamol in mannitol (Perfalgan?).
プロパセタモール 上流と下流の製品情報
原材料
準備製品