ANTI-PHOSPHO-TAU (PSER199/202)
ANTI-PHOSPHO-TAU (PSER199/202) 物理性質
- 貯蔵温度 :
- -20°C
- 外見 :
- 緩衝グリセロール水溶液
ANTI-PHOSPHO-TAU (PSER199/202) 価格
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ANTI-PHOSPHO-TAU (PSER199/202) 化学特性,用途語,生産方法
使用
Anti-phospho-Tau (pSer
199/202) antibody (diluted 1:1000 in PBS containing 0.3% Triton X-100 and 0.5% BSA) can be used in immunocytochemistry for identification of protein aggregates. It can also be used as primary antibody (diluted 1: 3000) in immunohistochemistry.
一般的な説明
Tau proteins are known as microtubule-associated phosphoprotein (MAP) and express mainly in neurons of central nervous system. It has a crucial role in tubulin polymerization and facilitates microtubules assembly and stability. The biological activity of tau proteins depends on degree of its phosphorylation. Anti-phospho-Tau (pSer
199/202) antibody can be used in microarray and western blotting. It can also be used in immunoblotting. Rabbit anti- phospho-Tau (pSer
199/202) antibody reacts specifically with human Tau (pSer
199/202) (45-68 kD).
Biochem/physiol Actions
Tau (τ) plays an essential role in the assembly and maintenance of microtubule structure. Deletion of tau (τ) results in developmental delay and learning disability. The gene expression is associated with the development of Alzheimer′s disease (AD). Genetic variation in τ gene increases the risk of susceptibility to the sporadic tauopathies, progressive supranuclear palsy (PSP) and corticobasal degeneration.
ANTI-PHOSPHO-TAU (PSER199/202) 上流と下流の製品情報
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ANTI-PHOSPHO-TAU (PSER199/202) 生産企業
Global( 3)Suppliers
- ANTI-PHOSPHO-TAU (PSER199/202)
- Anti-phospho-Tau (pSer199/202) antibody produced in rabbit