1-アリル-2-チオ尿素 化学特性,用途語,生産方法
外観
白色～わずかにうすい褐色, 結晶性粉末
溶解性
水、エタノールに可溶。エーテルに微溶。ベンゼンに不溶。水及びエタノールに溶けやすく、ジエチルエーテルに溶ける。
用途
有機合成原料、生化学研究用。
化学的特性
white crystals or powder. Melting point 76～78.5 ℃, relative density is 1.110, soluble in water and ethanol, slightly soluble in ethanol, insoluble in benzene, with a garlic odor. It is used as an additive for cyanide-free copper plating to increase the brightness and corrosion resistance of plated products.
使用
N-Allylthiourea is a nitrification inhibitor used in the study on the transformation of diclofenac, naproxen and bisoprolol under aerobic and anaerobic conditions. It is also used in medicine to minimize scar tissue in order to fight against a type of dermatitis. Further, it inhibits the growth of transplanted tumors in mice. It acts as a chelating agent. In addition, it is used in cosmetics, preservative and in organic synthesis.
製造方法
In the presence of potassium iodide, in ethanol solution, chloropropene is reacted with sodium thiocyanide to form allyl isothiocyanate, which is then ammoniated in ammonium hydroxide solution, concentrated, cooled and crystallized, filtered, washed, and recrystallized in ethanol or water to produce Allylthiourea.
定義
ChEBI: Allylthiourea is a thiourea with a prop-2-enyl group attached to one of the amines. It has a role as a metabolite. It is functionally related to a thiourea.
一般的な説明
White crystalline solid with a slight garlic odor.
空気と水の反応
Soluble in water.
反応プロフィール
Allylthiourea may react vigorously with strong oxidizing agents. Can react exothermically with reducing agents (such as alkali metals and hydrides) to release gaseous hydrogen. May react exothermically with both acids and bases. May generate flammable gases in combination with aldehydes, nitrides, and hydrides. Incompatible with peroxides and acid halides.
健康ハザード
SYMPTOMS: Contact eczema due to sensitization in humans has been reported.
火災危険
Flash point data are not available for Allylthiourea, but Allylthiourea is probably combustible.
純化方法
Recrystallise it from H2O. It is soluble in 30 parts of cold H2O, and it is soluble in EtOH but insoluble in *C6H6. It has also been recrystallised from acetone, EtOH or ethyl acetate, after decolorising with charcoal. The white crystals have a bitter taste with a slight garlic odour and are TOXIC. An unstable crystalline form is obtained by recrystallising from the melt. [McCrone et al. Anal Chem 21 421 1949, Beilstein 4 IV 1072.]
1-アリル-2-チオ尿素 上流と下流の製品情報
原材料
準備製品