抗ニトロチロシン抗体 ウサギ宿主抗体 化学特性,用途語,生産方法
使用
Anti-Nitrotyrosine antibody produced in rabbit has been used in:
- immunoblotting
- enzyme-linked immunosorbent assay (ELISA)
- immunohistochemistry
- immunofluorescence immunocytochemistry
- confocal microscopy
- immunofluorescent staining
一般的な説明
Peroxinitrite (ONOO-), a potent oxidant linked to cellular oxidative damage, is an important member of the family of reactive oxygen and nitrogen species, rapidly generated
in vivo from nitric oxide and superoxide anion. Nitrotyrosine?is a product of tyrosine nitration, that is facilitated by reactive nitrogen species.
Biochem/physiol Actions
Peroxynitrite has been shown to promote the nitration of tyrosine residues in proteins, and oxidation of redox metal centers, DNA, lipids and cysteine and methionine residues in proteins, suggesting that it plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease, including neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), in the pathogenesis of asthma, atherosclerosis and a variety of conditions precipitated by endothelial injury.
抗ニトロチロシン抗体 ウサギ宿主抗体 上流と下流の製品情報
原材料
準備製品