タダラフィル-D3
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- CAS番号.
- 960226-55-5
- 化学名:
- タダラフィル-D3
- 别名:
- タダラフィル-D3
- 英語名:
- Tadalafil-d3
- 英語别名:
- Tadalafil-d3;[2H3]-Tadalafil;PubChem ID: 46782966;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;Tadalafil D3Q: What is
Tadalafil D3 Q: What is the CAS Number of
Tadalafil D3 Q: What is the storage condition of
Tadalafil D3 Q: What are the applications of
Tadalafil D3
- CBNumber:
- CB32104260
- 化学式:
- C22H18N3O4
- 分子量:
- 388.39602
- MOL File:
- 960226-55-5.mol
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タダラフィル-D3 物理性質
- 融点 :
- 281-283°C
- 貯蔵温度 :
- -20°C Freezer
- 溶解性:
- クロロホルム（微量）、DMSO（微量）
- 外見 :
- 個体
- 色:
- ホワイトからオフホワイト
- 安定性：:
- メタノール中で不安定
- InChI:
- InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3
- InChIKey:
- WOXKDUGGOYFFRN-PDIFIXMTNA-N
- SMILES:
- c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r|
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
タダラフィル-D3 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
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富士フイルム和光純薬株式会社(wako)
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W01TRCT004510 |
タダラフィル-d3
Tadalafil-d3 |
960226-55-5 |
1mg |
￥66300 |
2024-03-01 |
購入 |
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富士フイルム和光純薬株式会社(wako)
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W01TRCT004510 |
タダラフィル-d3
Tadalafil-d3 |
960226-55-5 |
10mg |
￥509700 |
2024-03-01 |
購入 |
タダラフィル-D3 化学特性,用途語,生産方法
説明
Tadalafil-d
3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC
50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC
50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC
50 = 11 nM).
In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
化学的特性
Tadalafil-d3 is White Solid
使用
Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.
タダラフィル-D3 上流と下流の製品情報
原材料
準備製品
タダラフィル-D3 生産企業
Global( 47)Suppliers
960226-55-5(タダラフィル-D3)キーワード:
- 960226-55-5
- Tadalafil-d3
- Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-
- PubChem ID: 46782966
- [2H3]-Tadalafil
- Tadalafil D3Q: What is
Tadalafil D3 Q: What is the CAS Number of
Tadalafil D3 Q: What is the storage condition of
Tadalafil D3 Q: What are the applications of
Tadalafil D3
- タダラフィル-D3