トリメチルすずクロリド 化学特性,用途語,生産方法
外観
白色～ほとんど白色粉末～結晶
溶解性
水、エタノール及びアセトンに溶ける。
用途
有機合成用試薬。
使用上の注意
不活性ガス封入
化学的特性
WHITE CRYSTALS
使用
Trimethyltin chloride is an organotin reagent widely used in transferring trimethylstannyl groups onto the substrates to synthesize various organostannanes. Trimethylstannyl compounds derived from this reagent, are extensively used in the palladium-catalyzed Stille coupling reactions.
一般的な説明
Solid.
反応プロフィール
TRIMETHYLTIN CHLORIDE is in the family of tin compounds widely used as stabilizers for plastics, additives to paint(as antifouling agents). Some have catalytic properties. Examples include butyl tin, dibutyl tin oxide. Their main hazard is associated with their high toxicity, in skin adsorption or inhalation.
危険性
A deadly poison. A reproductive hazard.
健康ハザード
Trimethyltin chloride and other organotin compounds are highly toxic by ingestion,
inhalation, or skin contact. Trimethyltin chloride can cause irritation and burns of the
skin and eyes. Organotin compounds can affect the central nervous system. The
degree of toxicity is greatest for compounds with three or four alkyl groups attached
to tin. Diand monoalkyltin compounds are moderately toxic. The toxicity diminishes
as the size of the alkyl groups increases. Thus, the oral LD50s in rats are as follows:
dimethyltin dichloride, 74 to 237 mg/kg; tributyltin chloride, 122 to 349 mg/kg;
dibutyltin oxide, 487 to 520 mg/kg; trioctyltin chloride, >4000 mg/kg.
Organotin compounds have been shown to cause reproductive effects in laboratory
animals.
火災危険
When heated to decomposition, TRIMETHYLTIN CHLORIDE emits toxic fumes of chlorides. Avoid decomposing heat.
燃焼性と爆発性
Not a significant fire hazard. Emits toxic fumes in fire.
安全性プロファイル
A deadly poison by
intravenous route. Experimental
reproductive effects. See also TIN
COMPOUNDS. When heated to
decomposition it emits toxic fumes of Cl-.
不和合性
Trimethyltin chloride and other organotin halides react with water to produce
hydrogen halides. Organotin hydrides react with water to produce hydrogen gas,
which is flammable and explosive.
廃棄物の処理
Excess trimethyltin chloride or other organotin compound and waste material containing this
substance should be placed in an appropriate container, clearly labeled, and handled according
to your institution's waste disposal guidelines.
トリメチルすずクロリド 上流と下流の製品情報
原材料
準備製品
4-BROMO-2-(TRIFLUOROMETHYL)-5-METHOXYPYRIDINE
4,8-ビス(n-オクチルオキシ)-2,6-ビス(トリメチルスタンニル)ベンゾ[1,2-b:4,5-b']ジチオフェン
3,3'-ジブロモ-5,5'-ビス(トリメチルシリル)-2,2'-ビチオフェン
4,8-ビス[(2-エチルヘキシル)オキシ]-2,6-ビス(トリメチルスタンニル)ベンゾ[1,2-b:4,5-b']ジチオフェン