N2-Fmoc-N6-Boc-N6-メチル-Lys-OH
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH 物理性質
- 融点 :
- 85-87℃
- 沸点 :
- 665.4±55.0 °C(Predicted)
- 比重(密度) :
- 1.200
- 貯蔵温度 :
- -20°C
- 溶解性:
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- 外見 :
- Powder
- 酸解離定数(Pka):
- 3.88±0.21(Predicted)
- InChIKey:
- JHMSFOFHTAYQLS-QHCPKHFHSA-N
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH 価格
もっと(11)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-2685 |
Fmoc-Lys(Me,Boc)-OH |
951695-85-5 |
1g |
￥100000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-2685 |
Fmoc-Lys(Me,Boc)-OH |
951695-85-5 |
5g |
￥300000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-2685 |
Fmoc-Lys(Me,Boc)-OH |
951695-85-5 |
10g |
￥480000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4033388 |
Fmoc-Lys(Boc)(Me)-OH |
951695-85-5 |
250mg |
￥126000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4033388 |
Fmoc-Lys(Boc)(Me)-OH |
951695-85-5 |
1g |
￥378000 |
2024-03-01 |
購入 |
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH 化学特性,用途語,生産方法
説明
Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.
使用
- Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
- Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
- Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.
一般的な説明
Fmoc protected N-methylated lysine
参考文献
http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htm
https://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH 上流と下流の製品情報
原材料
準備製品
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH 生産企業
Global( 130)Suppliers
N2-Fmoc-N6-Boc-N6-メチル-Lys-OH スペクトルデータ(FT-IR)
951695-85-5(N2-Fmoc-N6-Boc-N6-メチル-Lys-OH)キーワード:
- 951695-85-5
- N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-TERT-BUTYLOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE
- N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-T-BUTYL-OXYCARBONYL-N-EPSILON-METHYL-L-LYSINE
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-T-BUTOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE
- N-ALPHA-FMOC-N-EPSILON,EPSILON-T-BOC-METHYL-L-LYSINE
- N-ALPHA-FMOC-N-EPSILON-METHYL-N-EPSILON-T-BOC-L-LYSINE
- FMOC-LYS(BOC)(ME)-OH
- FMOC-LYSINE(BOC)(ME)-OH
- FMOC-L-LYS(BOC, ME)-OH
- N'-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-methyl-L-lysine
- (S)-1-(9H-fluoren-9-yl)-10,13,13-trimethyl-3,11-dioxo-2,12-dioxa-4,10-diazatetradecane-5-carboxylic acid
- FMoc-N-epsilon-Methyl-N-epsilon-t-Boc-L-lysine
- Fmoc-Lys(Me,Boc)-OH, >=97%
- Nalpha-Fmoc-Nepsilon-methyl-Nepsilon-Boc-L-lysine
- Fmoc-Lys(Me,Boc)-OH Novabiochem
- (9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Boc, Me)-OH
- Fmoc-Lys(Me,Boc)-OH
N-Fmoc-N'-Boc-N'-Methyl-Lysine
- N6-[(tert-Butoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl-L-Lysine, 97%
- L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl-
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoicaci
- FMOC-LYS(BOC)(ME)-OH USP/EP/BP
- Boc-L-Lys(Fmoc)(Me)-OH
- N'-tert-butyloxycarbonyl-N-fluorenylmethoxycarbonyl-N'-methyl-L-lysine
- (2S)-6-{[(tert-butoxy)carbonyl](methyl)amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid
- FMOC-LYS(ME,BOC)-OH
- Fmoc-Lys(Me,Boc)
- N6-Boc-N2-Fmoc-N6-methyl-L-lysine
- N2-(((9H-fluorene-9-yl)methoxy)oxo)-N6-(tertbutyloxyoxo)-N6-methyl-L-lysine
- Fmoc-Lys(Me,Boc)-OH,95%
- N2-Fmoc-N6-Boc-N6-メチル-Lys-OH
- (2S)-6-{[(tert-ブトキシ)カルボニル](メチル)アミノ}-2-({[(9H-フルオレン-9-イル)メトキシ]カルボニル}アミノ)ヘキサン酸