2-ベンゾオキサゾリノン 化学特性,用途語,生産方法
外観
白色～灰褐色, 結晶性粉末～粉末又は塊
溶解性
エタノールに溶け、水にほとんど溶けない。
用途
有機合成原料。
化学的特性
light beige to brown-grey powder. insoluble in water, soluble in benzene, chlorobenzene and other solvents.
定義
ChEBI: 2-benzoxazolinone is a member of the class of benzoxazoles that is 2,3-dihydro-1,3-benzoxazole carrying an oxo group at position 2. It has a role as an allelochemical and a phytoalexin.
製造方法
2-benzoxazolinone synthesis method: add o-aminophenol, urea and solvent chlorobenzene into the reaction kettle, protect with nitrogen, the reaction temperature is 50～132 ℃, the reaction time is 6h, after the reaction is completed, it is cooled with ice brine, crystallized, Filter the finished product. It is also possible to use o-aminophenol to react with phosgene in the solvent chlorobenzene, quickly pass phosgene within 20 ~ 40 ° C, then heat up to 100 ~ 130 ° C, and then pass phosgene at a lower speed, after the reaction is completed, pass nitrogen to catch up. Phosgene, after work-up, can also obtain 2-benzoxazolinone.
一般的な説明
2-Benzoxazolinone is a phytoanticipin and its biotransformation by endophytic fungi isolated from
Aphelandra tetragona was studied. 2-Benzoxazolinone is a natural chemical produced by rye (
Secale cereale) and has strong phytotoxic properties.
安全性プロファイル
Poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic fumes of NOx.
2-ベンゾオキサゾリノン 上流と下流の製品情報
原材料
準備製品