JAK3 INHIBITOR VI

JAK3 INHIBITOR VI 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

JAK3 INHIBITOR VI 化学特性,用途語,生産方法

一般的な説明

A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC₅₀ = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC₅₀ = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.

Biochem/physiol Actions

Cell permeable: yes

JAK3 INHIBITOR VI 上流と下流の製品情報

原材料

準備製品

JAK3 INHIBITOR VI 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58

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• 856436-16-3
• JAK3 INHIBITOR VI
• JI6