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RO 08-2750

化学構造式
37854-59-4
CAS番号.
37854-59-4
化学名:
别名:
英語名:
RO 08-2750
英語别名:
RO 08-2750;7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE;7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde;2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde;Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-;growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI
CBNumber:
CB3844689
化学式:
C13H10N4O3
分子量:
270.24
MOL File:
37854-59-4.mol
MSDS File:
SDS

RO 08-2750 物理性質

貯蔵温度 :
Store at -20°C
溶解性:
≤2.7mg/ml in DMSO
外見 :
solid
色:
Orange

安全性情報

RO 08-2750 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC2272
Ro 08-2750 		37854-59-4 1mg ￥35000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC2272
Ro 08-2750 		37854-59-4 10mg ￥76000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC2272
Ro 08-2750 		37854-59-4 50mg ￥312000 2024-03-01 購入

RO 08-2750 化学特性,用途語,生産方法

使用

Ro 08-2750 is a TrkA inhibitor and NGF-induced apoptosis inhibitor.

生物活性

Non-peptide inhibitor of NGF that binds the NGF dimer (K D ~ 1 μ M) possibly causing a conformational change. Inhibits binding selectively to p75 NTR at submicromolar concentrations and to both p75 NTR and TrkA at higher concentrations (> 5 μ M). Prevents NGF-induced apoptosis in SK-N-MC cells.

RO 08-2750 上流と下流の製品情報

原材料

準備製品

RO 08-2750 生産企業

Global( 38)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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Changzhou PBpharmaceutical R&D Co.,Ltd 		0519-83990708
info@pbpharm.com CHINA 498 58
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InvivoChem 		+1-708-310-1919 +1-13798911105
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Aladdin Scientific 		+1-833-552-7181
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185
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EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
Shanghai Shanyuan pharmaceutical technology co., LTD 021-31761238 13167072949
 3146446224@qq.com China 1609 55
Changzhou PBpharmaceutical R&D Co.,Ltd 0519-83990708
lxy2046@yeah.net China 480 55

37854-59-4()キーワード:

1,3-ジヒドロ-3-[(1-メチル-1H-インドール-3-イル)メチレン]-2H-ピロロ[3,2-B]ピリジン-2-オン 7,8,10-トリメチル-2,3,4,10-テトラヒドロピリミド[4,5-b]キノキサリン-2,4-ジオン
  • 37854-59-4
  • 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde
  • RO 08-2750
  • 7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE
  • Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-
  • growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI
  • 7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde
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