1,3-ジクロロ-2-プロパノン 化学特性,用途語,生産方法
外観
白色~ほとんど白色, 結晶~結晶性粉末
溶解性
水、エタノール及びアセトンに溶けやすい。
用途
有機合成原料。
化学的特性
White or colorless crystals
使用
1,3-Dichloroacetone was used as acceptor substrate in the cross-aldol reaction with donor substrates such as acetone, cyclopentanone and cyclohexanon
一般的な説明
A crystalline solid. Denser than water and insoluble in water. Inhalation of dust or powder may cause adverse health reactions.
空気と水の反応
Insoluble in water.
反応プロフィール
A halogenated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
健康ハザード
1,3-Dichloroacetone may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution.
火災危険
When heated to decomposition, 1,3-Dichloroacetone emits highly toxic fumes of chlorides. 1,3-Dichloroacetone may burn but does not ignite readily. Container may explode in heat of fire.
安全性プロファイル
Poison by inhalation. Mutationdata reported. A systemic irritant by ingestion andinhalation routes. Dangerous; whenheated to decomposition it emits highly toxic fumes ofCl-.
職業ばく露
Formerly extensively used in textiles
(especially polyester fabrics) and still employed in polyurethane
foams, textile backcoating and adhesives.
輸送方法
UN2649 1,3-Dichloroacetone, Hazard class: 6.1;
Labels: 6.1—Poisonous materials.
純化方法
Crystallise it from CCl4, CHCl3 or *benzene and/or distil under vacuum [Conant & Quayle Org Synth Coll Vol I 211 1941, Hall & Sirel J Am Chem Soc 74 836 1952]. It is dimorphic [Daasch & Kagarise J Am Chem Soc 77 6156 1955]. The oxime has m 130-131o, b 106o/25mm [Arzneimittel-Forsch 8 638 1958]. [Beilstein 1 IV 3219.]
1,3-ジクロロ-2-プロパノン 上流と下流の製品情報
原材料
準備製品