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クエン酸ラニチジンビスマス

クエン酸ラニチジンビスマス 化学構造式
128345-62-0
CAS番号.
128345-62-0
化学名:
クエン酸ラニチジンビスマス
别名:
クエン酸ラニチジンビスマス
英語化学名:
Ranitidinebismuthcitrate
英語别名:
Pylorid;Gastrimuto;Ranitidine bismutrex;RANTIDINEBISMUTHCITRATE;2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
CBNumber:
CB41073641
化学式:
C19H30N4O10S
分子量:
506.53
MOL File:
128345-62-0.mol

クエン酸ラニチジンビスマス 物理性質

CAS データベース:
128345-62-0

安全性情報

クエン酸ラニチジンビスマス 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

クエン酸ラニチジンビスマス 化学特性,用途語,生産方法

効能

消化性潰瘍薬, H2受容体拮抗薬

説明

Ranitidine bismuth citrate, a novel salt formed from ranitidine and a bismuth citrate complex, is a new agent introduced in the United Kingdom for the treatment of duodenal and benign gastric ulcers, for eradication of Helicobacfer pylori, and for prevention of relapse of duodenal ulcer when administered in combination with an antibiotic such as clarithromycin or amoxicillin. Ranitidine is a potent histamine H2-receptor antagonist with ability to inhibit gastric acid secretion. Other type of agents such as tripotassium dicitrato bismuthate exert their therapeutic effects in peptic ulceration by providing a protective coating to the ulcer crater, stimulating endogenous prostaglandin production, and inhibiting pepsin activity. More significantly, they inhibit micro-organism Helicobacfer pylori, a prevalent, specifically human pathogen associated with gastritis and gastric ulcers. The title compound possesses a novel combination of properties of the above two types of drugs and displays excellent therapeutic efficacy in clinical studies. Ranitidine bismuth citrate is being investigated for use in gastritis and non-ulcerating dyspepsia, acute healing of gastrointestinal ulcer and in prevention of the recurrence of peptic ulcer disease.

Originator

Glaxo Wellcome (United Kingdom)

使用

Antagonist (to histamine H2receptors).

brand name

Tritec (GlaxoSmithKline);Pylorid.

危険性

A poison by ingestion.

クエン酸ラニチジンビスマス 上流と下流の製品情報

原材料

準備製品


クエン酸ラニチジンビスマス 生産企業

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