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エポチロンD

エポチロンD 化学構造式
189453-10-9
CAS番号.
189453-10-9
化学名:
エポチロンD
别名:
エポチロンD
英語化学名:
Epothilone D
英語别名:
Epo D;KOS 862;NSC 703147;Epothilone D;12,13-Deoxyepo;Desoxyepothilone B;Epothilone D (KOS-862);12,13-Desoxyepothilone B;(4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9,13-pentaMethyl-16-[(1E)-1-Methyl-2-(2-Methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione;(3S,7S,14S,15S,16R)-3,15-Dihydroxy-2,2,10,14,16-pentamethyl-7-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-6-oxacyclohexadec-9-ene-1,5-dione
CBNumber:
CB41214330
化学式:
C27H41NO5S
分子量:
491.68
MOL File:
189453-10-9.mol

エポチロンD 物理性質

融点 :
63-66°C
比旋光度 :
D22 -61.3° (c = 2.5 in methanol)
貯蔵温度 :
-20°C Freezer

安全性情報

エポチロンD 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTE6356 エポチロンD
Epothilone D
189453-10-9 1mg ¥13700 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01LKTE6356 エポチロンD
Epothilone D
189453-10-9 5mg ¥30000 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01LKTE6356 エポチロンD
Epothilone D
189453-10-9 10mg ¥52400 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01LKTE6356 エポチロンD
Epothilone D
189453-10-9 25mg ¥112400 2018-12-26 購入

エポチロンD 化学特性,用途語,生産方法

化学的特性

White Foam

使用

Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.

定義

ChEBI: An epithilone that is epithilone C in which the hydrogen at position 13 of the oxacyclohexadec-13-ene-2,6-dione macrocycle has been replaced by a methyl group.

エポチロンD 上流と下流の製品情報

原材料

準備製品


エポチロンD 生産企業

Global( 64)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22064 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20743 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2548 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24212 60
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8416 58
Accendatech Co., LTD. 022-83718541 022-83718543
022-83718543-802 sales@accendatech.com, chuanjiang.qiu@accendatech.com China 334 58
Shanghai Witofly Chemical Co.,Ltd
sales@witofly.com China 2874 52
BOC Sciences
info@bocsci.com United States 10518 65
Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-66771942
0411-66771945 sales@meilune.com China 4097 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

189453-10-9(エポチロンD)キーワード:


  • 189453-10-9
  • (4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9,13-pentaMethyl-16-[(1E)-1-Methyl-2-(2-Methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione
  • 12,13-Desoxyepothilone B
  • Epo D
  • KOS 862
  • NSC 703147
  • Epothilone D (KOS-862)
  • Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (4S,7R,8S,9S,13Z,16S)-
  • Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl -16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-, (4S-(4R*,7S,8R*,9R*,1 3Z,16R*(E)))-
  • (3S,7S,14S,15S,16R)-3,15-Dihydroxy-2,2,10,14,16-pentamethyl-7-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-6-oxacyclohexadec-9-ene-1,5-dione
  • Epothilone D
  • Desoxyepothilone B
  • 12,13-Deoxyepo
  • エポチロンD
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