DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト
DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト 物理性質
- 貯蔵温度 :
- Inert atmosphere,Store in freezer, under -20°C
- 外見 :
- 粉
- 酸解離定数(Pka):
- 7.87±0.43(Predicted)
- 色:
- ホワイトからオフホワイト
- InChIKey:
- FFXHNCNNHASXCT-RFMFGJHUSA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| WGK Germany |
3 |
|
|
| HSコード |
29349990 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
呼吸器への刺激のおそれ |
特定標的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
|
|
|
| 注意書き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P301+P312 |
飲み込んだ場合：気分が悪い時は医師に連絡する こと。 |
| P302+P352 |
皮膚に付着した場合：多量の水と石鹸で洗うこと。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト 価格
もっと(13)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
A211050 |
DMT-2''O-TBDMS-rA(bz) ホスホロアミダイト configured for (?KTA? and OligoPilot?)
configured for (?KTA? and OligoPilot?) |
104992-55-4 |
2G |
￥28900 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
A211050 |
DMT-2''O-TBDMS-rA(bz) ホスホロアミダイト configured for (?KTA? and OligoPilot?)
DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for (?KTA? and OligoPilot?) |
104992-55-4 |
10g |
￥114000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
A211040 |
DMT-2''O-TBDMS-rA(bz) ホスホロアミダイト configured for MerMade
configured for MerMade |
104992-55-4 |
5G |
￥53000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
A211040 |
DMT-2''O-TBDMS-rA(bz) ホスホロアミダイト configured for MerMade
DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for MerMade |
104992-55-4 |
10g |
￥145000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
A211000 |
DMT-2'O-TBDMS-rA(bz) ホスホロアミダイト
DMT-2′O-TBDMS-rA(bz) Phosphoramidite |
104992-55-4 |
100g |
￥1060000 |
2024-03-01 |
購入 |
DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト 化学特性,用途語,生産方法
使用
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite can be used as Organic synthesis intermediates and pharmaceutical intermediates are mainly used in laboratory research and development processes and chemical production processes.
合成
To a solution of 72 (12.0 g, 15.2 mmoi) in DIPEA (15 ml) and DCM (30 mL) is added DMAP (744 mg, 6.09 rnrnol) and 2cyanoethyl JV.Ndiisopropylchlorophosphoramidite (5.41 g, 22.9 rnmoi) at 25 ℃. After stirring for 2 hours, the mixture is purified directly by basic silica gel column chromatography (EAIPE 1/4 toi/1) to give DMT-2'O-TBDMS-rA(bz) Phosphoramidite as a white solid (13.0 g. 86% yield)
DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト 上流と下流の製品情報
原材料
準備製品
DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト 生産企業
Global( 172)Suppliers
104992-55-4(DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト)キーワード:
- 104992-55-4
- DMT-2′O-TBDMS-rA(bz) Phosphoramidite
- 2'-TBDMS -Bz-rA-CE-Phosphoramidite
- 5'-DMT-2'-O-TBDMS- N6-Benzoyl-Adenosine Phosphoramidite
- (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
- REF DUPL: 2'-TBDMS-rA(N-Bz)Phosphoramidite
- N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
- 5'-O-(4,4'-DiMethoxy)-N6-benzoyl-2'-O-(t-butyl diMethylsilyl)adenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoraMidite
- 5'-O-DMT-2'-O-TDMS-N6-Bz-Adenosine-3'-CED PhosphoraMidite
- Adenosine, N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]
- 2’-TBDMS-rA(N-Bz) Phosphoramidite
- 5'-O-DMT-2'-TBDMS-rA(N-Bz)-3'-CEDPA
- N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
- 5'-DMT-2'-TBDMS-rA(N-Bz) Phosphoramidite
- N6-Benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- TIANFU-CHEM N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- 5'-Dimethoxytrityl-N-benzoyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimet...
- N-diisopropyl)phosphoramidite
- N-Benzoyl-5-O-(4
- 4-Dimethoxytrityl)-2-O-[(tert-butyl)dimethylsilyl]adenosine-3-(2-cyanoethyl-N
- 5'-DMT-2'-TBDMS-N6-Bz-rA phosphoramidite
- 2'-TBDMS-A CEP
- 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-Adenosine 3'-CE phosphoramidite
- 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite
- Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- 8-Aza-7-deaza-A CEP
- 5'-O-DMT-2'-O-tert-Butyldimethylsiyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite
- Bz-rA Phosphoramidite
- DMT-2'O-TBDMS-RA(BZ) ホスホロアミダイト