Chenopodium oil 化学特性,用途語,生産方法
化学的特性
Colorless or yellowish oil; characteristic
penetrating odor; bitterish burning taste. Soluble in 3–10 volumes of 70% alcohol (inferior and adulterated oils
do not yield a clear solution).
天然物の起源
Found in the flowers and fruit of the plant C. ambrosioides and C. ambrosioides L. var. anthelminticum (L.) A. Gray (Fam. Chenopodiaceae) (Guenther, 1952).
使用
Chenopodium Oil may cause an increase in the erythrocyte count by provoking contraction of the spleen. Chenopodium Oil has been used for the treatment of strongylidosis in horses.
製造方法
By steam distillation from the overground parts of the flowering and fruiting plant, C. ambrosioides (Guenther, 1952).
薬理学
In tests of antispasmodic activity, a saturated aqueous solution of chenopodium
oil showed musculotropic spasmolytic activity against BaCl2-induced spasms in rat duodenum, had
a clear antihistaminic action in guinea-pig ileum and inhibited nicotine-induced spasms in rabbit
jejunum (Debelmas & Rochat, 1967). Frogs, toads and guinea-pigs responded to chenopodium oil
by a decrease in the rate and amplitude of the heart beat, ascribed to vagus excitation and myocardium
intoxication (Donatelli, 1935).
代謝
The oil is readily absorbed from the gastro-intestinal tract. It is partially eliminated
in the lungs, but excretion via the urine or faeces does not appear to have been reported (Goodman
& Gilman, 1960). Traces of ascaridole were found in the stomach and intestinal tract of a 14-monthold baby who died from poisoning with chenopodium oil (Meie, 1952).
Chenopodium oil 上流と下流の製品情報
原材料
準備製品