ベンセラジド·塩酸塩
ベンセラジド·塩酸塩 物理性質
- 融点 :
- 146°C
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- H2O: 10 mg/mL
- 外見 :
- 個体
- 色:
- ホワイトからオフホワイト
- PH:
- pH(10g/L, 25℃) : 4.0～5.0
- 水溶解度 :
- 水、ジメチルスルホキシド、メタノールに可溶。エタノール、アセトンに不溶。
- Sensitive :
- Light Sensitive
- 極大吸収波長 (λmax):
- 272nm(HCl aq.)(lit.)
- Merck :
- 14,1050
- InChIKey:
- ULFCBIUXQQYDEI-UHFFFAOYSA-N
- CAS データベース:
- 14919-77-8(CAS DataBase Reference)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01W0102-1451 |
ベンセラジド塩酸塩 95.0+% (Titration)
Benserazide Hydrochloride 95.0+% (Titration) |
14919-77-8 |
1g |
￥8500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01W0102-1451 |
ベンセラジド塩酸塩 95.0+% (Titration)
Benserazide Hydrochloride 95.0+% (Titration) |
14919-77-8 |
5g |
￥35000 |
2024-03-01 |
購入 |
|
東京化成工業
|
B4108 |
ベンセラジド塩酸塩 >97.0%(HPLC)(T)
Benserazide Hydrochloride
>97.0%(HPLC)(T) |
14919-77-8 |
1g |
￥5700 |
2024-03-01 |
購入 |
|
東京化成工業
|
B4108 |
ベンセラジド塩酸塩 >97.0%(HPLC)(T)
Benserazide Hydrochloride
>97.0%(HPLC)(T) |
14919-77-8 |
5g |
￥19100 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
Y0002115 |
ベンセラジド 塩酸塩 European Pharmacopoeia (EP) Reference Standard
European Pharmacopoeia (EP) Reference Standard |
14919-77-8 |
Y0002115 |
￥19100 |
2024-03-01 |
購入 |
ベンセラジド·塩酸塩 化学特性,用途語,生産方法
外観
白色～黄褐色, 結晶性粉末～粉末
溶解性
水に可溶水に溶ける。
用途
デカルボキシラーゼ(脱炭酸酵素)の阻害剤。
効能
パーキンソン病治療薬, ドパ脱炭酸酵素阻害薬
説明
Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.
化学的特性
White Crystalline Solid
使用
Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.
定義
ChEBI: A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of park
nsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions whe
given alone.
一般的な説明
Benserazide is a peripheral decarboxylase inhibitor.
ベンセラジド·塩酸塩 上流と下流の製品情報
原材料
準備製品
ベンセラジド·塩酸塩 生産企業
Global( 432)Suppliers
14919-77-8(ベンセラジド·塩酸塩)キーワード:
- 14919-77-8
- RO 4-4602
- BENSERAZIDE HYDROCHLORIDE
- DL-SERINE 2[(2,3,4-TRIHYDROXYPHENYL)-METHYL] HYDRAZIDE HYDROCHLORIDE
- DL-SERINE 2-[(2,3,4-TRIHYDROXYPHENYL)METHYL]HYDRAZIDE HCL
- 2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide monohydrochloride
- 2-(2,3,4-trihydroxybenzyl)hydrazide,monohydrochloride,dl-serin
- dl-serine,2-((2,3,4-trihydroxyphenyl)methyl)hydrazide,monohydrochloride
- dl-serine2-(2,3,4-trihydroxybenzyl)hydrazinehydrochloride
- BENSERAZIDE HYDROCHLORIDE EP2000
- BENSERAZIDE HYDROCHLORIDE \ PERIPHERAL D
- Benserazide HCl (Serazide)
- Benserazide HCl (Ro 4-4602)
- dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
- BENPARIZDE
- DL-Serine N2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
- N'-(DL-Seryl)-N''-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride
- N-(DL-Seryl)-N'-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride
- Ro 4-4602/001
- Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, monohydrochloride (8CI)
- Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, monohydrochloride
- 2-(2,3,4-TRIHYDROXYBENZYL)HYDRAZIDE
- Benserazide hydrochloride(Benserazide HCl)
- Benserazide hydrochloride (Serazide)
- 2-AMino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
- N'-(2,3,4-trihydroxybenzyl)-2-amino-3-hydroxypropanehydrazide, hydrochloride(1:1)
- (S)-2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
- 31796-68-6
- Benserazide hydrochlo
- Madopa (Hoffmann-LaRoche)
- NCGC00093698-03
- ベンセラジド·塩酸塩
- 塩酸ベンセラジド
- rac-1-[(R*)-2-アミノ-3-ヒドロキシ-1-オキソプロピル]-2-(2,3,4-トリヒドロキシベンジル)ヒドラジン·塩酸塩
- ベンセラジド塩酸塩
- DL-セリン 2-(2,3,4-トリヒドロキシベンジル)ヒドラジド塩酸塩
- ベンセラジド 塩酸塩
- ベンセラジド塩酸塩 (JP17)
- ベンセラジド・塩酸塩
- rac-1-[(R*)-2-アミノ-3-ヒドロキシ-1-オキソプロピル]-2-(2,3,4-トリヒドロキシベンジル)ヒドラジン・塩酸塩