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アトルバスタチン

アトルバスタチン 化学構造式
134523-00-5
CAS番号.
134523-00-5
化学名:
アトルバスタチン
别名:
アトルバスタチン
英語化学名:
Atorvastatin
英語别名:
Cardyl;Atrovastitne;025-83371857;ATORVASTATIN;ATORVASTATIN CA;Atorvastatin acid;ATORVASTATIN(LIPITOR);Atorvastatin free ACID;ATORVASTATIN DIPROTECTED;ATORVASTATIN CALCIUM SALT
CBNumber:
CB4239912
化学式:
C66H68CaF2N4O10
分子量:
1155.34
MOL File:
134523-00-5.mol

アトルバスタチン 物理性質

融点 :
176-178°C
酸解離定数(Pka):
pKa 4.46(H2O t=30 Iuncontrolled) (Uncertain)
CAS データベース:
134523-00-5(CAS DataBase Reference)

安全性情報

主な危険性  Xn
Rフレーズ  20/21/22-36/37/38
Sフレーズ  26-36
HSコード  35040000
有毒物質データの 134523-00-5(Hazardous Substances Data)

アトルバスタチン 価格 もっと(5)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01FLC079255
(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
134523-00-5 250mg ¥21100 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01FLC079255
(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
134523-00-5 1g ¥34300 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01MAS075942
(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
134523-00-5 5g ¥91500 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01FLC079255
(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
134523-00-5 10g ¥170900 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01MAS075942
(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
134523-00-5 1g ¥30400 2018-12-26 購入

アトルバスタチン 化学特性,用途語,生産方法

効能

脂質異常症治療薬, HMG-CoA還元酵素阻害薬

化学的特性

white Crystalline powder

使用

antihyperlipoproteimic;HMG-CoA reductase inhibition

brand name

Lipitor (Pfizer).

一般的な説明

Atorvastatin, [R-(R*,R*)]-2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-lH-pyrrole-1-heptanoic acid(Lipitor), also possesses the heptanoic acid side chain,which is critical for inhibition of HMG-CoA reductase.Although the side chain is less lipophilic than the lactoneform, the high amount of lipophilic substitution causes this agent to have a slightly higher level of CNS penetration thanpravastatin, resulting in a slight increase in CNS side effects.Even so, its CNS profile is much lower than that of lovastatin.Atorvastatin is marketed as a combination therapywith amlodipine under the trade name Norvasc for managementof high cholesterol and high blood pressure.

一般的な説明

Cerivastatin (Baycol) is one of the neweragents in this class of cholesterol-lowering agents. However,it carries a higher incidence of rhabdomyolysis and, as a result,was voluntarily withdrawn from the market by its manufacturerin 2001.

アトルバスタチン 上流と下流の製品情報

原材料

準備製品


アトルバスタチン 生産企業

Global( 154)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21751 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23967 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6370 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58

134523-00-5(アトルバスタチン)キーワード:


  • 134523-00-5
  • Atorvastatin (Subject to Patent free)
  • (3r,5r)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid
  • Atorvastatin&Ats-5Ats-8Ats-9M4L1
  • (bR,dR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-
  • (3R,5R)-2-(4-Fluorophenyl)-3,5-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-
  • Cardyl
  • Atrovastitne
  • ATORVASTATIN(LIPITOR)
  • [R-(R^<*>^,R^<*>^)]-2-(4-Fluorophenyl)- β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylarnino)carbonyl]-1H.Pyrrole-1- heptanoic acid
  • (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxy-enanthic acid
  • (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbaMoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
  • Atorvastatin acid
  • Atorvastatin free ACID
  • Atorvastatin CalciuM Tablets
  • ATORVASTATIN DIPROTECTED
  • 025-83371857
  • (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
  • (3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydr
  • (3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dih
  • ATORVASTATIN
  • ATORVASTATIN CA
  • ATORVASTATIN CALCIUM SALT
  • アトルバスタチン
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