rel-1α*,2α*,3β*,4α*,5β*,6β*-ヘキサクロロシクロヘキサン 化学特性,用途語,生産方法
化学的特性
BHC is a white-to-brownish crystalline solid
with a musty, phosgene-like odor.
物理的性質
Brownish to white monoclinic prisms, crystalline solid or powder with a phosgene-like odor
(technical grade). An odor threshold concentration of 88 μg/kg was reported by Sigworth (1964).
使用
α-1,2,3,4,5,6-Hexachlorocyclohexane is an organochloride which is one of the isomers of hexachlorocyclohexane and is an byproduct of insecticide Lindane (L465990).
一般的な説明
White crystalline powder.
空気と水の反応
Insoluble in water.
反応プロフィール
Halogenated aliphatic compounds, such as ALPHA-HCH, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
健康ハザード
ACUTE/CHRONIC HAZARDS: Carcinogen. Toxic. Irritant. Hazardous decomposition product.
火災危険
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
安全性プロファイル
ConfEmed carcinogen
with experimental carcinogenic,
tumorigenic, and neoplastigenic data. Poison
by ingestion. Mutation data reported. When
heated to decomposition it emits toxic
fumes of Cl-. See also BENZENE
HEXACHLORIDE and other
benzenehexachloride entries.
職業ばく露
The major commercial usage of BHC
is based upon its insecticidal properties. α-BCH is used as
an Agricultural chemical, pesticide, pharmaceutical, and
veterinary drug. The 7-isomer has the highest acute toxic ity, but the other isomers are not without activity. It is gen erally advantageous to purify the 7-isomer from the less
active isomers. The γ-isomer acts on the nervous system of
insects, principally at the level of the nerve ganglia. As a
result, lindane has been used against insects in a wide range
of applications including treatment of animals, buildings,
humans for ectoparasites, clothes; water for mosquitoes;
living plants; seeds and soils. Some applications have been
abandoned due to excessive residues, e.g., stored food stuffs. By voluntary action, the principal domestic producer
of technical grade BHC requested cancellation of its BHC
registrations on September 1, 1976. As of July 21, 1978, all
registrants of pesticide products containing BHC voluntar ily canceled their registrations or switched their former
BHC products to lindane formulations.
環境運命予測
Biological. Clostridium sphenoides degraded α-BHC to δ-3,4,5,6-tetrachloro-1-cyclo hexane (Heritage and MacRae, 1977a). In four successive 7-day incubation periods, α-
BHC (5 and 10 mg/L) was recalcitrant to degradation in a settled domestic wastewater
inoculum (Tabak et al., 1981).
Soil. Under aerobic conditions, indigenous microbes in contaminated soil produced
pentachlorocyclohexane. However, under methanogenic conditions, α-BHC was converted
to chlorobenzene, 3,5-dichlorophenol and the tentatively identified compound 2,4
Photolytic. When an aqueous solution containing α-BHC was photooxidized by UV
light at 90–95°C, 25, 50 and 75% degraded to carbon dioxide after 4.2, 24.2 and 40.0
hours, respectively (Knoevenagel and Himmelreich, 1976). In basic, aqueous solution
Chemical/Physical. Emits very toxic chloride fumes when heated to decomposition
(Lewis, 1990). α-BHC will hydrolyze via trans-dehydrochlorination of the axial chlorines
resulting in the formation of hydrochloric acid and the intermediate 1,3,4,5,6-pentachlo rocyclo-hexene. The intermediate will undergo further hydrolysis resulting in the formation
of 1,2,3-trichlorobenzene, 1,2,4-trichlorobenzene and hydrochloric acid (Kollig, 1993).
輸送方法
UN2761 Organochlorine pesticides, solid, toxic,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
純化方法
Crystallise it from EtOH. Purify it also by zone melting. Possible CANCER AGENT, TOXIC. [: Beilstein 1 H 23, : Beilstein 5 I 8, many isomers : Beilstein 5 III 41, 5 IV 55.]
不和合性
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Decomposes on contact
with powdered iron, aluminum, zinc, and on contact with
strong bases producing trichlorobenzene.
廃棄物の処理
A process has been developed
for the destructive pyrolysis of benzene hexachloride @
400 500℃ with a catalyst mixture which contains 5 10%
of either cupric chloride, ferric chloride; zinc chloride; or
aluminum chloride on activated carbon.
rel-1α*,2α*,3β*,4α*,5β*,6β*-ヘキサクロロシクロヘキサン 上流と下流の製品情報
原材料
準備製品