PDE4D Inhibitor, GEBR-7b - Calbiochem

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CAS番号.
化学名:
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英語名:
PDE4D Inhibitor, GEBR-7b - Calbiochem
英語别名:
PDE4D Inhibitor, GEBR-7b - Calbiochem
CBNumber:
CB44817714
化学式:
分子量:
0
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Mol file

PDE4D Inhibitor, GEBR-7b - Calbiochem 物理性質

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PDE4D Inhibitor, GEBR-7b - Calbiochem 価格

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PDE4D Inhibitor, GEBR-7b - Calbiochem 化学特性,用途語,生産方法

一般的な説明

A cell permeable, potent, and selective oxime PDE4D inhibitor (IC50 = 0.67 μM) which displays much reduced activities toward other PDE4 isoforms. It is shown to cause a significant 40% increase in extracellular cAMP in the hippocampus of freely moving rats in vivo at 100 μM, but has no effect on Aβ levels. This compound elicits cognitive enhancement in vivo at the optimum dose of 0.003 mg/kg in both mice and rat models, and unlike rolipram, does not cause emesis-like behavior in rodents.

PDE4D Inhibitor, GEBR-7b - Calbiochem 上流と下流の製品情報

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PDE4D Inhibitor, GEBR-7b - Calbiochem 生産企業

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