ナラトリプタン塩酸塩
ナラトリプタン塩酸塩 物理性質
- 融点 :
- 234-236°C
- 貯蔵温度 :
- -20°C Freezer
- 溶解性:
- H2O: ≥10mg/mL
- 外見 :
- 粉
- 色:
- ホワイトからオフホワイト
- InChIKey:
- AWEZYKMQFAUBTD-UHFFFAOYSA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
主な危険性 |
Xi |
|
|
Rフレーズ |
36 |
|
|
Sフレーズ |
26 |
|
|
WGK Germany |
3 |
|
|
HSコード |
2935904000 |
|
|
絵表示(GHS) |
|
注意喚起語 |
警告 |
危険有害性情報 |
コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
|
注意書き |
P305+P351+P338 |
眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TRCN378730 |
ナラトリプタン塩酸塩
Naratriptan Hydrochloride |
143388-64-1 |
50mg |
¥77100 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TRCN378730 |
ナラトリプタン塩酸塩
Naratriptan Hydrochloride |
143388-64-1 |
5mg |
¥17300 |
2023-06-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TRCN378730 |
ナラトリプタン塩酸塩
Naratriptan Hydrochloride |
143388-64-1 |
25mg |
¥37400 |
2023-06-01 |
購入 |
Sigma-Aldrich Japan
|
N1415 |
ナラトリプタン 塩酸塩 ≥98% (HPLC)
Naratriptan hydrochloride ≥98% (HPLC) |
143388-64-1 |
10mg |
¥13300 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
1457469 |
ナラトリプタン 塩酸塩 United States Pharmacopeia (USP) Reference Standard
Naratriptan hydrochloride United States Pharmacopeia (USP) Reference Standard |
143388-64-1 |
125mg |
¥73700 |
2024-03-01 |
購入 |
ナラトリプタン塩酸塩 化学特性,用途語,生産方法
外観
白色~ほとんど白色粉末~結晶
効能
抗片頭痛薬, 血管収縮薬, セロトニン受容体作動薬
商品名
アマージ (グラクソ・スミスクライン)
説明
Naramig was launched in Germany, Sweden and the UK for use in migraine.
It is chemically available via a number of related synthetic routes all having about
three steps starting from 5-bromoindole. It is a new serotonin 5-HT
1B/1D receptor
antagonist with modest affinity for 5-HT
1a, and very weak affinity for 5-HT
3 receptors. It
has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors,
dopamine, neurokinin NK
1, and opiate receptors. It mediates
vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces
neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It
has a 6- and 3-fold greater affinity for 5-HT
1B, and 5-HT
1D, receptors, respectively, than
sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of
headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig
had no clinical effects on blood pressure or heart rate, had a long duration of action
with very good tolerability, and has high oral bioavailability.
化学的特性
Beige Solid
使用
Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches
ナラトリプタン塩酸塩 上流と下流の製品情報
原材料
準備製品
ナラトリプタン塩酸塩 生産企業
Global( 164)Suppliers
ナラトリプタン塩酸塩 スペクトルデータ(1HNMR)
143388-64-1(ナラトリプタン塩酸塩)キーワード:
- 143388-64-1
- NARATRIPTAN HYDROCHLORIDE (125 MG)F0C3600.998MG/MG(AI)
- Amerge.
- Naramig
- Naratriptan Hydrochloride
- N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide Hydrochloride
- N-Methyl-3-(1-methylpiperidin-4-yl)-1H-indole-5-ethanesulfonamide hydrochloride
- Naratriptan monohydrochloride
- Naratriptan Hydrochloride (125 mg)
- 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl
- N-Methyl-2-(3-(1-Methylpiperidin-4-yl)-1H-indol-5-yl)ethanesulfonaMide hydrochloride
- Nariptan Hydrochloride
- Naratriptan Nitrate USP
- 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl)-, hydrochloride (1:1)
- GR-85548A
- N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
- 1H-Indole-5-ethanesulfonamide,N-methyl-3-(1-methyl-4-piperidinyl)-,hydrochloride
- NARATRIPTAN HYDROCHLORIDE (125 MG)F0C36099%8MG/MG(AI)
- GR-85548A hydrochloride
- Naratriptan Hydrochloride USP/EP/BP
- Naratryptan hydrochloride
- Naratriptan HCl (GR-85548A HCl)
- Naratriptan HydrochlorideQ: What is
Naratriptan Hydrochloride Q: What is the CAS Number of
Naratriptan Hydrochloride Q: What is the storage condition of
Naratriptan Hydrochloride
- Naratriptan Hydrochloride (1457469)
- N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethane-1-sulfonamide hydrochloride
- ナラトリプタン塩酸塩
- ナラトリプタン 塩酸塩
- ナラトリプタン塩酸塩 (JAN)