Lubiprostone
Lubiprostone 物理性質
- 融点 :
- 56-59°C
- 沸点 :
- 539.1±50.0 °C(Predicted)
- 比重(密度) :
- 1.143±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- -20°C
- 溶解性:
- クロロホルム（微量）、DMSO（微量）、メタノール（微量）
- 酸解離定数(Pka):
- 4.77±0.10(Predicted)
- 外見 :
- 粉
- 色:
- 白からベージュ
Lubiprostone 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
SML1173 |
ルビプロストン ≥98% (HPLC)
Lubiprostone ≥98% (HPLC) |
136790-76-6 |
10mg |
￥25100 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML1173 |
ルビプロストン ≥98% (HPLC)
Lubiprostone ≥98% (HPLC) |
136790-76-6 |
50mg |
￥101000 |
2024-03-01 |
購入 |
Lubiprostone 化学特性,用途語,生産方法
化学的特性
Lubiprostone is a white, odorless crystals or crystalline powder and is very soluble in ether and ethanol, and practically insoluble in hexane and water. It is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.
使用
Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
主な応用
Lubiprostone is a locally acting chloride channel activator for the treatment of gastrointestinal disorders.
Biochem/physiol Actions
Lubiprostone is a bicyclic fatty acid that activates ClC-2 and CFTR chloride channels. Some reports suggest that lubiprostone opens CFTR or both CFTR and ClC-2 through interactions with the prostaglandin receptor EP4. Lubiprostone is used clinically to treat idiopathic chronic constipation and irritible bowel syndrome.
Lubiprostone 上流と下流の製品情報
原材料
準備製品
Lubiprostone 生産企業
Global( 220)Suppliers
136790-76-6()キーワード:
- 136790-76-6
- Lubiprostone API
- 7-[(1r,4r,6r,9r)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid
- lubiprostone
- (11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid
- Ru 0211
- (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid
- C13707
- Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-
- Lubiprostone, >=99%
- Rubiprostone
- SPI 0211;UNII-7662KG2R6K;AMITIZA LUBIPROSTONE
- 16,16-Difluoro-11alpha-hydroxy-9,15-dioxoprostan-1-oic Acid
- Lubiprostone USP/EP/BP
- Lubiprostone (SPI-0211
- LubiprostoneQ: What is
Lubiprostone Q: What is the CAS Number of
Lubiprostone Q: What is the storage condition of
Lubiprostone Q: What are the applications of
Lubiprostone
- TIANFU-CHEM - Lubiprostone
- (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid
- Rubyprostone
- Lubiprostone
CAS