四硝酸エリトリチル 化学特性,用途語,生産方法
効能
冠血管拡張薬, 心房性ナトリウム利尿ペプチド受容体作動薬
化学的特性
Crystals. Soluble in alcohol, ether, and glycerol; insoluble in water.
使用
Vasodilator
(coronary). Cardilate (Glaxo Wellcome{) [Name previously
used: Erythrol Tetranitrate.].
定義
ChEBI: Erythritol in which each of the hydroxy groups has been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to nitroglycerin. It is usually used diluted with lactose or other suitable inert excipients, in order to mini
ise the risk of explosion; undiluted erythrityl tetranitrate can be exploded by percussion or excessive heat.
危険性
Severe explosion risk when shocked or heated.
純化方法
Crystallise cordite from EtOH. It explodes on percussion at ~220-460o and is a vasodilator. [Beilstein 1 III 2358, 1 IV 2809.]
四硝酸エリトリチル 上流と下流の製品情報
原材料
準備製品