2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
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- CAS番号.
- 775351-54-7
- 化学名:
- 别名:
- 英語名:
- 2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
- 英語别名:
- 4-Cyano-3-methylphenylboronic acid pinacol ester;2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile;Benzonitrile, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber:
- CB51508470
- 化学式:
- C14H18BNO2
- 分子量:
- 243.11
- MOL File:
- 775351-54-7.mol
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2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
物理性質
- 沸点 :
- 368.7±35.0 °C(Predicted)
- 比重(密度) :
- 1.05±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
価格
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2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
化学特性,用途語,生産方法
合成
A mixture of dichloro[1 ,1 ,'-bis(diphenylphosphino)ferrocene] palladium (II) dichloromethane adduct (2.12 g, 2.55 mmol), potassium acetate (7.66 g, 76.5 mmol), and bis(pinacolato) diboron (7.12 g, 28.1 mmol) was flushed with nitrogen. 1 ,2- dimethoxyethane (130 ml ) and 4-bromo-2-methylbenzonitrile (5.00 g, 25.5 mmol) were added. The reaction was stirred at 80°C for 5 h. The reaction was cooled to room temperature and filtered through celite. The filtrate was diluted with ethyl acetate and washed with water. The organic layer was washed with brine, dried over magnesium sulfate and filtered. Silica gel was added and the mixture was concentrated. Finally, the crude material was purified by silica column chromatography eluting with a gradient of 0%- 45% ethyl acetate / heptane to give 2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile (5.07 g, 82%) as a white solid.
2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
上流と下流の製品情報
原材料
準備製品
2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
生産企業
Global( 25)Suppliers
775351-54-7()キーワード:
- 775351-54-7
- 4-Cyano-3-methylphenylboronic acid pinacol ester
- Benzonitrile, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile
- 2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile