塩酸イソクスプリン
塩酸イソクスプリン 物理性質
- 融点 :
- 203-204°
- 貯蔵温度 :
- Inert atmosphere,2-8°C
- 溶解性:
- 水またはエタノール（96%）にやや溶けにくく、塩化メチレンにほとんど溶けない。
- 酸解離定数(Pka):
- pKa 8.0 (Uncertain);9.8 (Uncertain)
- CAS データベース:
- 579-56-6(CAS DataBase Reference)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCI918150 |
イソクスプリン塩酸塩
Isoxsuprine Hydrochloride |
579-56-6 |
1g |
￥18300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCI918150 |
イソクスプリン塩酸塩
Isoxsuprine Hydrochloride |
579-56-6 |
10g |
￥29400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
PHR3190 |
イソクスプリン 塩酸塩 pharmaceutical secondary standard, certified reference material
pharmaceutical secondary standard, certified reference material |
579-56-6 |
500MG |
￥31500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
I0900000 |
イソクスプリン 塩酸塩 European Pharmacopoeia (EP) Reference Standard
Isoxsuprine hydrochloride European Pharmacopoeia (EP) Reference Standard |
579-56-6 |
i0900000 |
￥28300 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
1354003 |
イソクスプリン 塩酸塩 United States Pharmacopeia (USP) Reference Standard
Isoxsuprine hydrochloride United States Pharmacopeia (USP) Reference Standard |
579-56-6 |
200mg |
￥59000 |
2024-03-01 |
購入 |
塩酸イソクスプリン 化学特性,用途語,生産方法
効能
血管拡張薬, β2アドレナリン受容体作動薬
商品名
ズファジラン (第一三共); ズファジラン (第一三共)
説明
Isoxsuprine is an adrenergic receptor modulator that has α-adrenergic receptor (α-AR) antagonist and β-AR agonist properties. It induces vasodilation of isolated equine common digital artery strips precontracted with norepinephrine, indicating an α-AR effect, and induces relaxation of isolated fowl cecum, an effect that can be blocked by the β-AR antagonist propranolol (Item Nos.
23349 |
17291). Isoxsuprine has antinociceptive effects in an acetic acid writhing test in mice. It also inhibits oxytocin-induced contractions in isolated rat uterus (IC
50 = 9.15 μM). It delays labor onset in rats by 31.63 hours when administered at a dose of 10 mg/kg per day on days 13 to 21 of gestation but increases heart rate with increasing concentration.
化学的特性
White Solid
使用
As a vasilodator drug, Isoxsuprine Hydrochloride is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. Isoxsuprine Hydrochloride has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that Isoxsuprine Hydrochloride may be useful as a as a tocolytic agent in the treatment of preterm labour.
塩酸イソクスプリン 上流と下流の製品情報
原材料
準備製品
塩酸イソクスプリン 生産企業
Global( 123)Suppliers
579-56-6(塩酸イソクスプリン)キーワード:
- 579-56-6
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- 塩酸イソクスプリン
- イソクスプリン塩酸塩
- イソクスプリン 塩酸塩
- イソクスプリン塩酸塩 (JP17)
- イソクスプリン・塩酸塩
- ズファジラン