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チオストレプトン

チオストレプトン 化学構造式
1393-48-2
CAS番号.
1393-48-2
化学名:
チオストレプトン
别名:
ブリアマイシン;チオストレプトンA;チアクチン;チオストレプトン;チオストレプトン FROM STREPTOMYCES AZUREUS
英語化学名:
THIOSTREPTON
英語别名:
x146;a-8506;thiactin;bryamycin;THIOSTREPTON;THIOSTREPTION;antibioticx146;antibiotica8506;antibiotic6761-31;Thiostrepton (200 mg)
CBNumber:
CB5204768
化学式:
C72H85N19O18S5
分子量:
1664.89
MOL File:
1393-48-2.mol

チオストレプトン 物理性質

融点 :
248-257°C (dec.)
比旋光度 :
D23 -98.5° (glacial acetic acid); -61° (dioxane); -20° (pyridine)
比重(密度) :
1.0824 (rough estimate)
屈折率 :
1.6700 (estimate)
貯蔵温度 :
−20°C
溶解性:
Soluble in DMSO or chloroform
外見 :
Off-white powder
Merck :
13,9440

安全性情報

主な危険性  Xn
Rフレーズ  22
Sフレーズ  22-24/25
WGK Germany  3
RTECS 番号 XN6300100
10-21

チオストレプトン 価格 もっと(7)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTT3134 チオストレプトン
Thiostrepton
1393-48-2 1g ¥34700 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01LKTT3134 チオストレプトン
Thiostrepton
1393-48-2 5g ¥136500 2018-12-26 購入
Sigma-Aldrich Japan T8902 チオストレプトン from Streptomyces azureus ≥90% (HPLC)
Thiostrepton from Streptomyces azureus ≥90% (HPLC)
1393-48-2 1g ¥33300 2018-12-25 購入
富士フイルム和光純薬株式会社(wako) W01USP1663700 チオストレプトン
Thiostrepton
1393-48-2 200mg ¥75000 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01TRCT375150 チオストレプトン
Thiostrepton
1393-48-2 10mg ¥11300 2018-12-26 購入

チオストレプトン 化学特性,用途語,生産方法

化学的特性

Off-White Solid

使用

beta-adrenergic agonist

使用

Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ribosomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, that are central regulators in multidrug resistance. Thiostrepton is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.

使用

Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ribosomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, and TipAL and TipAS, that are central regulators in multidrug resistance. Thiostrepton is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.

使用

Natural antibiotic derived from Streptomyces.

使用

A protein synthesis-inhibiting antibiotic

定義

ChEBI: A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitu or agent.

チオストレプトン 上流と下流の製品情報

原材料

準備製品


チオストレプトン 生産企業

Global( 85)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1954 70
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32492 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9966 79
BOC Sciences
info@bocsci.com United States 10558 65
Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-66771942
0411-66771945 sales@meilune.com China 4143 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725;010-86181995
010-65763397 waley188@sohu.com China 12388 58
Haoyuan Chemexpress Co., Ltd. 86-21-58998985
(86) 21-58955996 apisales@chemexpress.com.cn China 7567 61
9ding chemical ( Shanghai) Limited 4009209199
86-021-52271987 sales@9dingchem.com China 22651 55

1393-48-2(チオストレプトン)キーワード:


  • 1393-48-2
  • Thiostrepton - CAS 1393-48-2 - Calbiochem
  • AlaninaMide,N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-isoleucyl-L-alanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-aMino-21-[(1S,2R)-1,2-dihydroxy-1-Methylpropyl]-14-ethylidene-3,4,4a,9,10,1
  • a-8506
  • antibiotic6761-31
  • antibiotica8506
  • antibioticx146
  • bryamycin
  • thiactin
  • Thiostrepton (200 mg)
  • BryaMycin, Thiactin, AlaninaMide, X 146, A 8506, 6761-31
  • Thiostrepton, froM StreptoMyces sp.
  • x146
  • THIOSTREPTON
  • thiostrepton from streptomyces azureus
  • Alaninamide, L-threonyl-(4S)-2-(1Z)-1-amino-1-propenyl-4,5-dihydro-4-thiazolecarbonyl-2-(1S,2S,3R)-1-amino-2,3-dihydroxy-2-methylbutyl-4-thiazolecarbonyl-2-(5R,6S)-6-2-(1S,2R)-1-amino-2-hydroxypropyl-4-thiazolyl-5-N-(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy
  • THIOSTREPTION
  • Thiostrepton, 96%, from Streptomyces sp.
  • ブリアマイシン
  • チオストレプトンA
  • チアクチン
  • チオストレプトン
  • チオストレプトン FROM STREPTOMYCES AZUREUS
  • ペプチド系抗生物質
  • 抗細菌薬
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