グアーガム 化学特性,用途語,生産方法
外観
白色～うすい褐色, 結晶性粉末～粉末
定義
本品は、グァー Cyamopsis tetragonoloba の胚乳から得られる多糖類である。
溶解性
水に溶ける。熱水に溶け、エタノール及びアセトンにほとんど溶けない。
解説
グアーガムは，マメ科植物［Cyamopsis tetragonoloba］の種子胚乳部の粉末．主成分グアランは，ガラクトースとマンノースのモル比2：1のガラクトマンナンの一種．直鎖状のマンノースにガラクトースの側鎖が結びついた多糖類。グアー豆に多く含まれる水溶性食物繊維であり、増粘剤、安定剤などの食品添加物として利用される。粘稠なコロイドを作るので，アイスクリームミックスパウダーや果汁の安定剤として用いる．小学館 デジタル大辞泉について 情報 | 凡例
化粧品の成分用途
結合剤、親水性増粘剤、乳化安定剤、香料
説明
Background. Guar gum, like locust bean gum, is a galactomannan
derived from the seed of a leguminous plant. The source of guar,
Cyamopsis tetragonolobus, is widely grown in Pakistan and India
as cattle feed, and was introduced to the United States as a cover
crop in 1903. The U.S. is now also a producer. It was not until
1953, however, that guar gum was produced on a commercial
scale, primarily as a replacement for locus bean gum in the paper,
textile and food industries. The most important property of guar
is the ability to hydrate rapidly in cold water to attain a very high
viscosity. In addition to the food industry, guar is used in the
mining, paper, textile, ceramic, paint, cosmetic, pharmaceutical,
explosive, and other industries.
Sources, Harvesting, and Producing Areas. The guar is a hardy
and drought-resistant plant which grows three to six feet high with
vertical stalks. The guar pods, which grow in clusters along the
vertical stems, are about six inches long and contain 6 to 9 seeds,
which are considerably smaller than locus bean seeds. As in the
case of locust bean gum, the endosperm, which comprises 35-42%.
化学的特性
The USP32–NF27 describes guar gum as a gum obtained from the
ground endosperms of Cyamopsis tetragonolobus (L.) Taub. (Fam.
Leguminosae). It consists chiefly of a high-molecular-weight
hydrocolloidal polysaccharide, composed of galactan and mannan
units combined through glycoside linkages, which may be described
chemically as a galactomannan. The PhEur 6.3 similarly describes
guar galactomannan as being obtained from the seeds of Cyamopsis
tetragonolobus (L.) Taub. by grinding the endosperms and
subsequent partial hydrolysis.
The main components are polysaccharides composed of Dgalactose
and D-mannose in molecular ratios of 1 : 1.4 to 1 : 2. The
molecule consists of a linear chain of b-(1!4)-glycosidically linked
manno-pyranoses and single a-(1→6)-glycosidically linked galactopyranoses.
Guar gum occurs as an odorless or nearly odorless, white to
yellowish-white powder with a bland taste.
物理的性質
Guar gum is a white to yellowish-white powder It is dispersible in either hot or cold water, forming a solution having a pH between 5.4 and 7.0 that may be converted to gel by the addition of a small amount of sodium borate.
天然物の起源
Guar gum is an annual found in India, the United States, and the tropics of Asia.
使用
guar gum has a coating action on the skin that allows for moisture retention. often used as a thickener and emulsifier in cosmetic formulations, guar gum is a polysaccharide found in the seeds of the guar plant. It is the nutrient material required by the developing plant embryo during germination. When the endosperm, once separated from the hull and embryo, is ground to a powder form, it is marketed as guar gum.
定義
A water-soluble plant mucilage obtained from the ground endosperms of Cyanopsis tetragonoloba,
cultivated in India and Pakistan as livestock feed, as well as in southwestern U.S. The water-soluble portion of the flour (85%) is called guaran and consists o
調製方法
Guar gum is obtained from the ground endosperm of the guar plant,
Cyamopsis tetragonolobus (L.) Taub. (Fam. Leguminosae), which is
grown in India, Pakistan, and the semiarid southwestern region of
the USA.
The seed hull can be removed by grinding, after soaking in
sulfuric acid or water, or by charring. The embryo (germ) is
removed by differential grinding, since each component possesses a
different hardness. The separated endosperm, containing 80%
galactomannan is then ground to different particle sizes depending
upon final application.
一般的な説明
Off-white to yellowish-white powder. Five to eight times the thickening power of starch. Water solutions are tasteless, odorless, and nontoxic and have a pale translucent gray color with neutral pH. Water solutions converted to gel by small amounts of borax.
空気と水の反応
The organic dusts can react violently when suspended in air in the presence of an ignitable source. . Insoluble in water.
反応プロフィール
Guar gum is a ether-alcohol derivative, the ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
健康ハザード
ACUTE/CHRONIC HAZARDS: When heated to decomposition Guar gum emits irritating fumes and smoke.
火災危険
Flash point data for Guar gum are not available. However, Guar gum is probably combustible.
応用例（製薬）
Guar gum is a galactomannan, commonly used in cosmetics, food
products, and pharmaceutical formulations. It has also been
investigated in the preparation of sustained-release matrix tablets
in the place of cellulose derivatives such as methylcellulose.
In pharmaceuticals, guar gum is used in solid-dosage forms as a
binder and disintegrant; in oral and topical products
as a suspending, thickening, and stabilizing agent; and also as a
controlled-release carrier. Guar gum has also been examined for use
in colonic drug delivery. Guar-gum-based three-layer matrix
tablets have been used experimentally in oral controlled-release
formulations.
Therapeutically, guar gum has been used as part of the diet of
patients with diabetes mellitus. It has also been used as an
appetite suppressant, although its use for this purpose, in tablet
form, is now banned in the UK.
安全性
Guar gum is widely used in foods, and oral and topical
pharmaceutical formulations. Excessive consumption may cause
gastrointestinal disturbance such as flatulence, diarrhea, or nausea.
Therapeutically, daily oral doses of up to 25 g of guar gum have
been administered to patients with diabetes mellitus.
Although it is generally regarded as a nontoxic and nonirritant
material, the safety of guar gum when used as an appetite
suppressant has been questioned. When consumed, the gum swells
in the stomach to promote a feeling of fullness. However, it is
claimed that premature swelling of guar gum tablets may occur and
cause obstruction of, or damage to, the esophagus. Consequently,
appetite suppressants containing guar gum in tablet form have been
banned in the UK. However, appetite suppressants containing
microgranules of guar gum are claimed to be safe. The use of
guar gum for pharmaceutical purposes is unaffected by the ban.
In food applications, an acceptable daily intake of guar gum has
not been specified by the WHO.
LD50 (hamster, oral): 6.0 g/kg
LD50 (mouse, oral): 8.1 g/kg
LD50 (rabbit, oral): 7.0 g/kg
LD50 (rat, oral): 6.77 g/kg
貯蔵
Aqueous guar gum dispersions have a buffering action and are
stable at pH 4.0–10.5. However, prolonged heating reduces the
viscosity of dispersions.
The bacteriological stability of guar gum dispersions may be
improved by the addition of a mixture of 0.15% methylparaben
and 0.02% propylparaben as a preservative. In food applications,
benzoic acid, citric acid, sodium benzoate, or sorbic acid may be
used.
Guar gum powder should be stored in a well-closed container in
a cool, dry place.
不和合性
Guar gum is compatible with most other plant hydrocolloids such
as tragacanth. It is incompatible with acetone, ethanol (95%),
tannins, strong acids, and alkalis. Borate ions, if present in the
dispersing water, will prevent the hydration of guar gum. However,
the addition of borate ions to hydrated guar gum produces cohesive
structural gels and further hydration is then prevented. The gel
formed can be liquefied by reducing the pH to below 7, or by
heating.
Guar gum may reduce the absorption of penicillin V from some
formulations by a quarter.
規制状況(Regulatory Status)
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (oral suspensions,
syrups, and tablets; topical preparations; vaginal tablets).
Also included in nonparenteral medicines licensed in the UK.
Included in the Canadian List of Acceptable Non-medicinal
Ingredients.
グアーガム 上流と下流の製品情報
原材料
準備製品