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SCH79797二塩酸塩

SCH79797二塩酸塩 化学構造式
1216720-69-2
CAS番号.
1216720-69-2
化学名:
SCH79797二塩酸塩
别名:
SCH79797二塩酸塩
英語名:
7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)
英語别名:
SCH 79797 (hydrochloride);N3-Cyclopropyl-7-(4-isopropylbenzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride;7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2);infarct,SCH79797 dihydrochloride,SCH-79797 dihydrochloride,SCH-79797,SCH79797,Inhibitor,inhibit,Nonpeptide,thrombin,wortmannin,SCH 79797,antiproliferative,platelets,Protease Activated Receptor (PAR),pro-apoptotic,thrombosis,Thrombin receptors,PAR1,cardioprotection,Apoptosis
CBNumber:
CB52627190
化学式:
C23H26ClN5
分子量:
407.95
MOL File:
1216720-69-2.mol

SCH79797二塩酸塩 物理性質

貯蔵温度 :
Store at 2-8°C, protect from light
溶解性:
Soluble to 25 mM in ethanol and to 50 mM in DMSO
外見 :
Powder

安全性情報

SCH79797二塩酸塩 価格 もっと(7)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC1592 SCH79797二塩酸塩
SCH 79797 Dihydrochloride 		1216720-69-2 10mg ￥90000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC1592 SCH79797二塩酸塩
SCH 79797 Dihydrochloride 		1216720-69-2 50mg ￥381000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCC988945
N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Dihydrochloride 		1216720-69-2 1mg ￥12400 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCC988945
N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Dihydrochloride 		1216720-69-2 5mg ￥22000 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCC988945
N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Dihydrochloride 		1216720-69-2 10mg ￥31600 2023-06-01 購入

SCH79797二塩酸塩 化学特性,用途語,生産方法

説明

SCH 79797 is a non-peptide antagonist of proteinase-activated receptor 1 (PAR1). It blocks binding of the high affinity thrombin receptor-activating peptide (haTRAP) (IC50 = 70 nM) as well as platelet aggregation induced by either haTRAP or α-thrombin (IC50 = 0.3 and 3 μM, respectively). SCH 79797 has no activity against PAR2, PAR4, or other receptors involved in platelet activation. It also blocks PAR1 activation on vascular smooth muscle cells and endothelial cells.

使用

N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine Dihydrochloride is a selective PAR1 antagonist which was shown to limit myocardial ischemia/reperfusion injury in rat hearts.

SCH79797二塩酸塩 上流と下流の製品情報

原材料

準備製品

SCH79797二塩酸塩 生産企業

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SCH79797二塩酸塩  スペクトルデータ(1HNMR)

7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)(1216720-69-2)1HNMR

1216720-69-2(SCH79797二塩酸塩)キーワード:

SCH 58261 N-β-D-グルコピラノシル-N-[2-(2-ナフチルオキシ)エチル]-4-(ヒドロキシアミノ)ベンゼンスルホンアミド 2-(2-フラニル)-7-[3-(4-メトキシフェニル)プロピル]-7H-ピラゾロ[4,3-e][1,2,4]トリアゾロ[1,5-c]ピリミジン-5-アミン (3R)-N-[3-(4-ピリジル)-1H-インダゾール-5-イル]-1-[2-[4-[4-(2-ピリミジニル)フェニル]-1-ピペラジニル]-2-オキソエチル]ピロリジン-3α-カルボアミド
  • 1216720-69-2
  • 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2)
  • SCH 79797 (hydrochloride)
  • infarct,SCH79797 dihydrochloride,SCH-79797 dihydrochloride,SCH-79797,SCH79797,Inhibitor,inhibit,Nonpeptide,thrombin,wortmannin,SCH 79797,antiproliferative,platelets,Protease Activated Receptor (PAR),pro-apoptotic,thrombosis,Thrombin receptors,PAR1,cardioprotection,Apoptosis
  • N3-Cyclopropyl-7-(4-isopropylbenzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride
  • SCH79797二塩酸塩
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