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RS102895 塩酸塩

RS102895 塩酸塩 化学構造式
1173022-16-6
CAS番号.
1173022-16-6
化学名:
RS102895 塩酸塩
别名:
RS102895 塩酸塩
英語名:
RS-102895 hydrochloride
英語别名:
3-trihydroxybenzene;RS-102895;RS 102895;RS102895;1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1)
CBNumber:
CB52729375
化学式:
C21H22ClF3N2O2
分子量:
426.86
MOL File:
1173022-16-6.mol

RS102895 塩酸塩 物理性質

貯蔵温度 :
Inert atmosphere,Room Temperature
溶解性:
DMF: 25 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
外見 :
Powder

安全性情報

RS102895 塩酸塩 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC2089 RS102895 塩酸塩
RS 102895 hydrochloride 		1173022-16-6 10mg ￥57000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC2089 RS102895 塩酸塩
RS 102895 hydrochloride 		1173022-16-6 50mg ￥240000 2024-03-01 購入

RS102895 塩酸塩 化学特性,用途語,生産方法

説明

The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC50 = 0.36 μM). It inhibits the related CCR1 receptor with an IC50 value of 17.8 μM and inhibits adrenergic α1a, α1d, and 5HT1A receptors with IC50 values of 0.13, 0.32, and 47 μM, respectively. RS 102895 prevents chemotaxis of THP-1 cells (IC50 = 1.7 μM) when MCP-1 is presented as a chemoattractant.

使用

RS 102895 Hydrochloride is used as a leukocyte infiltrate marker for rosacea diagnosis.

RS102895 塩酸塩 上流と下流の製品情報

原材料

準備製品

RS102895 塩酸塩 生産企業

Global( 54)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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InvivoChem 		+1-708-310-1919 +1-13798911105
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LEAP CHEM CO., LTD. 		+86-852-30606658
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Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208
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ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58

RS102895 塩酸塩  スペクトルデータ(1HNMR、MS)

RS-102895 hydrochloride(1173022-16-6)MSRS-102895 hydrochloride(1173022-16-6)1HNMR

1173022-16-6(RS102895 塩酸塩)キーワード:

ピリジン塩酸塩 塩酸アニリン トリメチルアミン塩酸塩 メチルアミン 塩酸塩
  • 1173022-16-6
  • Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride
  • 3-trihydroxybenzene
  • Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1)
  • RS-102895;RS 102895;RS102895
  • 1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride
  • RS102895 塩酸塩
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