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二ステアリン酸マグネシウム

二ステアリン酸マグネシウム 化学構造式
557-04-0
CAS番号.
557-04-0
化学名:
二ステアリン酸マグネシウム
别名:
ビス(オクタデカン酸)マグネシウム;ジステアリン酸マグネシウム;ビス(ステアリン酸)マグネシウム;ステアリン酸マグネシウム;ビスステアリン酸マグネシウム;二ステアリン酸マグネシウム;ステアリン酸Mg;ステアリン酸マグネシウム(II);オクタデカン酸マグネシウム;ステアリン酸マグネシウム, 3.0ΜM;ステアリン酸マグネシウム「製造専用」;ステアリン酸マグネシウム, 植物由来;ステアリン酸マグネシウム (JP17)
英語化学名:
Magnesium stearate
英語别名:
Dolomol;petracmg20nf;MAGENSIUM STEARATE;MAGNESIUM STEARATE;MEGNESIUM STEATATE;Magnesiumdistearat;stearatedemagnesium;magnesiumdistearate;MagnesiuM stearates;Magnesium Stearate Bp
CBNumber:
CB5330900
化学式:
C36H70MgO4
分子量:
591.24
MOL File:
557-04-0.mol

二ステアリン酸マグネシウム 物理性質

融点 :
200 °C(lit.)
比重(密度) :
1.028g/cm3
貯蔵温度 :
Store at RT.
溶解性:
alcohol: insoluble
外見 :
Fine Powder
色:
White
PH:
7 (H2O) (slurry)
水溶解度 :
Insoluble
Merck :
14,5690
BRN :
3919702
安定性::
Stable. Incompatible with strong oxidizing agents.
InChIKey:
DRJIJXNWSSRTTE-UHFFFAOYSA-M
CAS データベース:
557-04-0(CAS DataBase Reference)
EPAの化学物質情報:
Octadecanoic acid, magnesium salt(557-04-0)

安全性情報

主な危険性  Xi
Rフレーズ  36/37/38
Sフレーズ  26-37/39
WGK Germany  -
RTECS 番号 WI4390000
TSCA  Yes
HSコード  29157030
有毒物質データの 557-04-0(Hazardous Substances Data)
毒性 LD50 orally in Rabbit: > 2000 mg/kg
化審法 (2)-611
安衛法 57,57-2

二ステアリン酸マグネシウム 価格 もっと(18)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01AFAA16244 ステアリン酸マグネシウム
Magnesium stearate
557-04-0 250g ¥6040 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01AFAA16244 ステアリン酸マグネシウム
Magnesium stearate
557-04-0 1000g ¥18720 2018-12-26 購入
東京化成工業 S0238 ステアリン酸マグネシウム(II)
Magnesium(II) Stearate
557-04-0 25g ¥1600 2018-12-04 購入
東京化成工業 S0238 ステアリン酸マグネシウム(II)
Magnesium(II) Stearate
557-04-0 250g ¥2400 2018-12-04 購入
関東化学株式会社(KANTO) 24076-2A ステアリン酸マグネシウム
Magnesium stearate
557-04-0 25g ¥4700 2018-12-13 購入

二ステアリン酸マグネシウム MSDS


Octadecanoic acid magnesium salt

二ステアリン酸マグネシウム 化学特性,用途語,生産方法

外観

白色〜ほとんど白色, 粉末

定義

本品は、ステアリン酸(*)のマグネシウム塩であり、次の化学式で表される。
参照表示名称:ステアリン酸

溶解性

水又はエタノール(99.5)にほとんど溶けない。

用途

塩化ビニル安定剤、錠剤の潤滑剤

用途

滑剤、安定剤、分散剤。

用途

医薬品・化粧品原料(滑沢剤)及び研究用。

用途

潤滑剤、撥水剤、安定剤、増粘剤、ツヤ消剤、離型剤、加硫促進剤、グリース基材、保険機能食品、化粧品原料(清浄用化粧品、頭髪用化粧品、基礎化粧品、メークアップ化粧品、芳香化粧品、日焼け?日焼け止め化粧品、爪化粧品、アイライナー化粧品、口唇化粧品、口腔化粧品、入浴用化粧品)

化粧品の成分用途

非水系増粘剤、抗ケーキング剤、増量剤、着色剤

効能

錠・カプセル潤滑剤

説明

Magnesium stearate, also called octa decanoic acid, magnesium salt, is a white substance, powder which becomes solid at room temperature. It has the chemical formula Mg(C18H35O2)2. It is a salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+). Magnesium stearate melts at about 120 °C, is not soluble in water, and is generally considered safe for human consumption at levels below 2500 mg/kg per day.In 1979, the FDA's Subcommittee on GRAS (generally recognized as safe) Substances (SCOGS) reported, "There is no evidence in the available information on ... magnesium stearate ... that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current and in the manner now practiced, or which might reasonably be expected in the future.".

化学的特性

Magnesium stearate is a compound of magnesium with a mixture of solid organic acids obtained from edible sources and consists chiefly of variable proportions of magnesium stearate and magnesium palmitate. It occurs as a fine, white, bulky powder having a faint, characteristic odor. It is unctuous and is free from grittiness. It is insoluble in water, in alcohol, and in ether. It conforms to the regulations of the U.S. Food and Drug Administration pertaining to specifications for salts of fatty acids derived from edible fat sources.

化学的特性

soft, light white powder(s); odorless, tasteless; nonflammable used in baby dusting powder(s) and as tablet lubricant [HAW93] [MER06]

化学的特性

Magnesium stearate is a very fine, light white, precipitated or milled, impalpable powder of low bulk density, having a faint odor of stearic acid and a characteristic taste. The powder is greasy to the touch and readily adheres to the skin.

使用

Magnesium Stearate is the magnesium salt of stearic acid which functions as a lubricant, binder, emulsifier, and anticaking agent. it is a white powder that is insoluble in water. it is used as a lubricant or die release in tableting pressed candies and is also used in sugar- less gum and mints.

使用

widely used in the fields of the plastic, mold-releasing agent for tablets (need meeting the medicine criterion), emulsifying agents of cosmetics. It also can conjugate with Ca Soap as stabilizer of PVC.

使用

In baby dusting powders; as tablet lubricant.

使用

Magnesium stearate is often used as a anti-adherent in the manufacture of medical tablets, capsules and powders. In this regard, the substance is also useful, because it has lubricating properties, preventing ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets; magnesium stearate is the most commonly used lubricant for tablets. Studies have shown that magnesium stearate may affect the release time of the active ingredients in tablets, etc., but not that it reduces the overall bioavailability of those ingredients. As a food additive or pharmaceutical excipient, its E number is E470b.
Magnesium stearate is also used to bind sugar in hard candies like mints, and is a common ingredient in baby formulas. In pure powder form, the substance can be a dust explosion hazard, although this issue is effectively insignificant beyond the manufacturing plants using it.
Magnesium stearate is manufactured from both animal and vegetable oils. Some nutritional supplements specify that the magnesium stearate used is sourced from vegetables.
Magnesium stearate is a major component of "bathtub rings." When produced by soap and hard water, magnesium stearate and calcium stearate both form a white solid insoluble in water, and are collectively known as "soap scum.".

製造方法

Magnesium stearate is created by the reaction of sodium stearate with magnesium sulfate.

調製方法

Magnesium stearate is prepared either by the interaction of aqueous solutions of magnesium chloride with sodium stearate or by the interaction of magnesium oxide, hydroxide, or carbonate with stearic acid at elevated temperatures.

定義

Mg(C18H35O2)2 or with one H2O. Technical grade contains small amounts of the oleate and 7% magnesium oxide, MgO.

応用例(製薬)

Magnesium stearate is widely used in cosmetics, foods, and pharmaceutical formulations. It is primarily used as a lubricant in capsule and tablet manufacture at concentrations between 0.25% and 5.0% w/w. It is also used in barrier creams.

安全性プロファイル

Slightly toxic by ingestion. Spontaneously combustible. When heated to decomposition it emits acrid smoke and toxic fumes.

安全性

Magnesium stearate is widely used as a pharmaceutical excipient and is generally regarded as being nontoxic following oral administration. However, oral consumption of large quantities may produce a laxative effect or mucosal irritation.
No toxicity information is available relating to normal routes of occupational exposure. Limits for heavy metals in magnesium stearate have been evaluated in terms of magnesium stearate worstcase daily intake and heavy metal composition.
Toxicity assessments of magnesium stearate in rats have indicated that it is not irritating to the skin, and is nontoxic when administered orally or inhaled.
Magnesium stearate has not been shown to be carcinogenic when implanted into the bladder of mice.
LD50 (rat, inhalation): >2 mg/L
LD50 (rat, oral): >10 g/kg

貯蔵

Magnesium stearate is stable and should be stored in a well-closed container in a cool, dry place.

不和合性

Incompatible with strong acids, alkalis, and iron salts. Avoid mixing with strong oxidizing materials. Magnesium stearate cannot be used in products containing aspirin, some vitamins, and most alkaloidal salts.

規制状況(Regulatory Status)

GRAS listed. Accepted as a food additive in the USA and UK. Included in the FDA Inactive Ingredients Database (oral capsules, powders, and tablets; buccal and vaginal tablets; topical preparapreparations; intravitreal implants and injections). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients. Listed on the US TSCA inventory.

二ステアリン酸マグネシウム 上流と下流の製品情報

原材料

準備製品


二ステアリン酸マグネシウム 生産企業

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557-04-0(二ステアリン酸マグネシウム)キーワード:


  • 557-04-0
  • stearatedemagnesium
  • MAGNESIUM STEARATE
  • MAGNESIUM OCTADECANOATE
  • MAGENSIUM STEARATE
  • STEARIC ACID MAGNESIUM SALT
  • OCTADECONIC ACID MAGNESIUM SALT
  • OCTADECANOIC ACID MAGNESIUM SALT
  • Magnesium Stearate Bp
  • MAGNESIUM STEARATE, TECH.
  • MAGNESIUM STEARATE EXTRA PURE DAB, PH. E UR., B.P., PH. FRANC.
  • MAGNESIUM STEARATE EXTRA PURE PHARMACOPOEIA
  • MAGNESIUM STEARATE 98%
  • Magnesium Stearate USP, Kosher
  • Magnesium Stearate Veg. NF
  • MagnesiumStearatePrecipitated
  • Magnesium stearate, 3.8-5.0% Mg
  • MAGNESIUMSTEARATE,FCC
  • MAGNESIUMSTEARATE,NF,BP,JP
  • MEGNESIUM STEATATE
  • dibasicmagnesiumstearate
  • Dolomol
  • magnesiumdistearate
  • Magnesiumstearatemedicinal
  • petracmg20nf
  • Magnesiumdistearat
  • STEARIC ACID, MAGNESIUM SALT, TECH.
  • MAGNESIUM STEARATE NF/FCC
  • MAGNESIUM STEARATE N.F.
  • Synpro Magnesium Stearate 90
  • Magnesium stearate, 3.8-5.0% magnesium
  • ビス(オクタデカン酸)マグネシウム
  • ジステアリン酸マグネシウム
  • ビス(ステアリン酸)マグネシウム
  • ステアリン酸マグネシウム
  • ビスステアリン酸マグネシウム
  • 二ステアリン酸マグネシウム
  • ステアリン酸Mg
  • ステアリン酸マグネシウム(II)
  • オクタデカン酸マグネシウム
  • ステアリン酸マグネシウム, 3.0ΜM
  • ステアリン酸マグネシウム「製造専用」
  • ステアリン酸マグネシウム, 植物由来
  • ステアリン酸マグネシウム (JP17)
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