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CP-424,174

化学構造式
210825-31-3
CAS番号.
210825-31-3
化学名:
别名:
英語名:
CP-424,174
英語别名:
CP-424,174;CP-424,174 >=98% (HPLC);N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide;CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR);N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide;Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
CBNumber:
CB54741315
化学式:
C22H29ClN2O4S
分子量:
452.99
MOL File:
210825-31-3.mol

CP-424,174 物理性質

比重(密度) :
1?+-.0.06 g/cm3(Predicted)
貯蔵温度 :
room temp
溶解性:
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
酸解離定数(Pka):
4.67±0.10(Predicted)
外見 :
粉
色:
白からベージュ

安全性情報

CP-424,174 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan PZ0347 ≥98% (HPLC)
CP-424,174 ≥98% (HPLC)		 210825-31-3 5mg ￥22500 2024-03-01 購入
Sigma-Aldrich Japan PZ0347 ≥98% (HPLC)
CP-424,174 ≥98% (HPLC)		 210825-31-3 25mg ￥87400 2024-03-01 購入

CP-424,174 化学特性,用途語,生産方法

Biochem/physiol Actions

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

CP-424,174 上流と下流の製品情報

原材料

準備製品

CP-424,174 生産企業

Global( 27)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
Zhengzhou Alfachem Co.,Ltd. 0371-53778726 18003825608
 liuxiaoyan@alfachem.cn China 1945 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2981 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
 info@SuperLan-chem.com China 9445 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 chaolaichem@foxmail.com China 6870 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
  • 210825-31-3
  • CP-424,174
  • N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
  • Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
  • CP-424,174 >=98% (HPLC)
  • N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide
  • CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR)
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