1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド

1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド 価格 もっと(1)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01CAY703218	GR NADPH	53-57-6	1ea	￥13400	2024-03-01	購入

1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド 化学特性,用途語,生産方法

使用

One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2?position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydrogenases. Present in living cells primarily in the r

定義

A coenzyme composed of ribosylnicotinamide 5′- phosphate coupled by pyrophosphate linkage to the 5′-phosphate adenosine 2′,5′-bisphosphate. The reduced from of NADP. It is an energy-storage form that can be transferred to the Calvin cycle where it participates in the production of carbohydrate.

生物学の機能

Nicotinamide adenine dinucleotide phosphate (NADPH) is used to maintain reduced glutathione (GSH) and thioredoxin (TRX). It is also well known as an essential electron donor and an indispensable cofactor for transferring and reserving reduction potential for numerous anabolic reactions. A growing body of evidence has shown that regeneration and maintenance of the cellular NADP(H) content is strongly implicated in various pathological conditions, such as diabetes, cardiovascular disease, neurodegenerative diseases, and aging, especially in tumorigenesis and cancer progression. Compared with non-tumor cells, tumor cells usually maintain high levels of NADPH to power redox defense and use biosynthetic reactions to sustain their rapid growth[1].

参考文献

[1] Huai-Qiang Ju. “NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications.” Signal Transduction and Targeted Therapy (2020): 231.

1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド 上流と下流の製品情報

原材料

準備製品

1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Maintain Biotech Co., Ltd.	+86-75589664337 +86-15112661142	cami@maintain-bio.com	China	66	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29067	58
Hong Kong Tiansheng New Material Trading Co., Ltd	+8617320695765	zxx@hktiansheng.com	China	981	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18455	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Maintain Biotech Co., Ltd.	755-89664337 19125366885	sales@maintain-bio.com	China	51	58
Suzhou Shunyixiang Biotechnology Co., Ltd	15973717224	526868882@qq.com	China	6	58
Shanghai Ruji Biology Technology Co., Ltd.	+86-21-65211385-8001 36031160	sales@shruji.com	China	3224	55

53-57-6(1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド)キーワード:

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• 53-57-6
• 25 MG ?-NICOTINAMIDE ADENINE DINUCLEOTIDEPHOSPHATE REDUCED.NA4-SALT AN.GR.
• adenosine5’-(trihydrogendiphosphate),2’-(dihydrogenphosphate),p’.fwdarw.5’
• -esterwith1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide
• dihydronicotinamide-adenine dinucleotide phosphate
• dihydrotriphosphopyridine nucleotide
• Adenosine 5-(trihydrogen diphosphate), 2-(dihydrogen phosphate), P?5-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl-3-pyridinecarboxamide
• [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
• Adenosine 5'-(Trihydrogen Diphosphate) 2'-(Dihydrogen Phosphate) P'-5'-Ester with 1,4-Dihydro-1--D-ribofuranosyl-3-pyridinecarboxamide
• Dihydrocodehydrogenase II
• -Nicotinamide-adenine-dinucleotide-phosphoric Acid
• Triphosphopyridine Nu
• NADPH2
• Reduced Co II
• Reduced triphosphopyridine nucleotide
• [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] hydrogen phosphate
• [[(2R,3S,4R,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4R,5R)-5-(6-azanylpurin-9-yl)-3-hydroxy-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate
• Na4 salt
• reduced
• 25 MG -NICOTINAMIDE ADENINE DINUCLEOTIDEPHOSPHATE REDUCED.NA4-SALT AN.GR. USP/EP/BP
• β-NADPH-d4
• ent-NADPH
• NADPN
• Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide
• NADPH,NICOTINAMIDE ADENINE DINUCLEOTIDEPHOSPHATE REDUCED
• β-Nicotinamide adenine dinucleotide phosphate Reduced form
• NADPH
• NADPH
• NADPH
• ジヒドロコデヒドロゲナーゼII
• 還元型補酵素II
• 1-[5-O-(2'-O-ホスホノ-5'-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド
• アデノシン2',5'-ビスりん酸5'-エステル1,4-ジヒドロ-1-β-D-リボフラノシルニコチンアミド
• 還元型CoII
• 還元型コデヒドロゲナーゼII
• 還元型ニコチンアミドアデニンジヌクレオチドりん酸
• 還元型コエンザイムII
• 還元型トリホスホピリジンヌクレオチド
• アデノシン2'-りん酸5'-[二りん酸P2-[1-(1,4-ジヒドロ-3-カルバモイルピリジン-1-イル)-1,5-ジデオキシ-β-D-ribo-ペントフラノース-5-イル]]
• アデノシン2'-りん酸5'-[二りん酸β-[1-(3-カルバモイル-1,4-ジヒドロピリジン-1-イル)-1,5-ジデオキシ-β-D-リボフラノース-5-イル]]
• {[(2R,3R,4R,5R)-2-(6-アミノ-9H-プリン-9-イル)-5-[({[({[(2R,3S,4R,5R)-5-(3-カルバモイル-1,4-ジヒドロピリジン-1-イル)-3,4-ジヒドロキシオキソラン-2-イル]メトキシ}(ヒドロキシ)ホスホリル)オキシ](ヒドロキシ)ホスホリル}オキシ)メチル]-4-ヒドロキシオキソラン-3-イル]オキシ}ホスホン酸
• アデノシン2′-りん酸5′-[二りん酸β-[1-(3-カルバモイル-1,4-ジヒドロピリジン-1-イル)-1,5-ジデオキシ-β-D-リボフラノース-5-イル]]
• アデノシン2′,5′-ビスりん酸5′-エステル1,4-ジヒドロ-1-β-D-リボフラノシルニコチンアミド
• アデノシン2′-りん酸5′-[二りん酸P2-[1-(1,4-ジヒドロ-3-カルバモイルピリジン-1-イル)-1,5-ジデオキシ-β-D-ribo-ペントフラノース-5-イル]]
• 1-[5-O-(2′-O-ホスホノ-5′-アデニリルオキシホスホニル)-β-D-リボフラノシル]-1,4-ジヒドロピリジン-3-カルボアミド
• 代謝産物