硫酸グアナドレル

硫酸グアナドレル 化学構造式
22195-34-2
CAS番号.
22195-34-2
化学名:
硫酸グアナドレル
别名:
グアナドレル硫酸塩;N-(1,4-ジオキサスピロ[4.5]デカン-2-イルメチル)グアニジン·0.5硫酸塩;硫酸グアナドレル;N-(1,4-ジオキサスピロ[4.5]デカン-2-イルメチル)グアニジン・0.5硫酸塩
英語名:
Guanadrel HeMisulfate
英語别名:
Anarel;Hylorel;U-28288D;CL-1388R;Hyloride;CHEBI:5556;Guanadrel HeMisulfate;GUANADREL SULFATE (200 MG);(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate;N-(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate
CBNumber:
CB5501416
化学式:
C10H19N3O2.H2O4S
分子量:
311.357
MOL File:
22195-34-2.mol

硫酸グアナドレル 物理性質

融点 :
213.5-215°

安全性情報

有毒物質データの 22195-34-2(Hazardous Substances Data)

硫酸グアナドレル 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

硫酸グアナドレル 化学特性,用途語,生産方法

効能

血圧降下薬, αアドレナリン受容体作動薬

使用

Guanadrel is an orally active postganglionic sympathetic inhibitor. Guanadrel HeMisulfate is used as an antihypertensive.

定義

ChEBI: A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthosta ic hypotension (dizzy spells on standing up or stretching).

一般的な説明

Guanadrel sulfate, (1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanadine sulfate (Hylorel), issimilar to guanethidine monosulfate in the manner in whichit reduces elevated blood pressure. It acts as a postganglionicadrenergic blocking agent by displacing norepinephrinein adrenergic neuron storage granules, therebypreventing release of the endogenous neurotransmitter onnerve stimulation. Guanadrel sulfate has a much shorterhalf-life (10 hours) than guanethidine monosulfate, whose half-life is measured in days. In the stepped-care approachto hypertension, guanadrel sulfate is usually a step 2 agent.

硫酸グアナドレル 上流と下流の製品情報

原材料

準備製品


硫酸グアナドレル 生産企業

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22195-34-2(硫酸グアナドレル)キーワード:


  • 22195-34-2
  • GUANADREL SULFATE (200 MG)
  • CL-1388R
  • U-28288D
  • (1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate
  • Anarel
  • Guanadrel HeMisulfate
  • Hylorel
  • N-(1,4-Dioxaspiro[4.5]dec-2-ylMethyl)guanidine Sulfate
  • 1-(1,4-Dioxaspiro[4.5]decan-2-ylmethyl)guanidine Sulfate
  • CHEBI:5556
  • Hyloride
  • グアナドレル硫酸塩
  • N-(1,4-ジオキサスピロ[4.5]デカン-2-イルメチル)グアニジン·0.5硫酸塩
  • 硫酸グアナドレル
  • N-(1,4-ジオキサスピロ[4.5]デカン-2-イルメチル)グアニジン・0.5硫酸塩
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