4'-メチルアセトフェノン 化学特性,用途語,生産方法
外観
無色～わずかにうすい黄色, 澄明の液体
定義
本品は、次の化学式で表される芳香族ケトンである。
溶解性
エタノール及びアセトンに溶けやすく、水にほとんど溶けない。
用途
石鹸等に使用される調合香料
化粧品の成分用途
香料
説明
4'-Methylacetophenone has a fruity, floral odor resembling acetophenone and a sweet, strawberry-like flavor. May be prepared
by slow addition of acetyl chloride to a mixture of toluene and
AlCl in an ice bath and under vacuum, maintaining the temperature
at +5°C and then letting it increase to +20°C.
化学的特性
4'-Methylacetophenone has
been identified in Brazilian rosewood oil and in pepper. It occurs as colorless crystals with a floral, sweet odor that is milder than that of acetophenone.
4-Methylacetophenone is prepared from toluene and acetic anhydride or acetyl
chloride by a Friedel–Crafts reaction. It is used for blossom notes in mimosaand
hawthorn-type perfumes, especially soap perfumes.
天然物の起源
Reported found in the essential oil distilled from the wood of Myrocarpus fastigiatus, Myrocarpus frondo sus, Bois de Rose. Also reported found in sour cherry, orange and grapefruit peel oil, black currants, guava, peach, blackberry,
celery, potato, tomato, mentha oils, pepper, parsley, smoked fish, cognac, parmesan cheese, cocoa, tea, soybean, cloudberry,
mango, cauliflower, broccoli, rice bran, buckwheat, dried bonito, cherimoya, calabash nutmeg and mastic gum leaf oil, cooked
cabbage, mandarin juice.
使用
4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.
定義
ChEBI: 4'-Methylacetophenone is an aromatic ketone. It is a metabolite found in or produced by Saccharomyces cerevisiae.
製造方法
By slow addition of acetyl chloride to a mixture of toluene and AlCl in an ice bath and under vacuum, maintaining the
temperature at +5°C and then letting it increase to +20°C.
一般的な説明
4′-Methylacetophenone is a clear colourless to pale yellowish liquid that occurs naturally in mango, tomato and orange.
安全性プロファイル
Moderately toxic by
ingestion. A human skin irritant. A
flammable liquid. When heated to
decomposition it emits acrid smoke and
irritating fumes. See also KETONES.
純化方法
Impurities, including the o-and m-isomers, are removed by forming the semicarbazone (m 212-213.5o) which, after repeated crystallisation, is hydrolysed to the ketone. [Brown & Marino J Am Chem Soc 84 1236 1962.] It can also be purified by distillation under reduced pressure, followed by low temperature crystallisation from isopentane. [Beilstein 7 IV 701.]
4'-メチルアセトフェノン 上流と下流の製品情報
原材料
準備製品
4-[4-(ブロモメチル)フェニル]-1,2,3-チアジアゾール
4-アセチル安息香酸
5-P-TOLYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE
4-(1,2,3-チアジアゾール-4-イル)ベンズアルデヒド
4-(4-メチルフェニル)-1,2,3-チアジアゾール
4-(1,2,3-チアジアゾール-4-イル)ベンゾイルクロリド
シアゾファミド
1-エチニル-4-メチルベンゼン
2-アミノ-4-(4-メチルフェニル)チオフェン-3-カルボン酸エチル
4-(1,2,3-THIADIAZOL-4-YL)BENZYLAMINE HYDROCHLORIDE
Naphthalene, 1,2,3,4-tetrahydro-1,6-dimethyl-4-(1-methylethyl)-, (1R,4R)-rel-
rac-(R*)-2-メチル-6-(p-トリル)-2-ヘプテン-4-オン
2-ブロモ-4'-メチルアセトフェノン
p-トルイル酸 メチル
3,5-ジブロモ-4-メチル安息香酸
2-アミノ-4-P-トリルチアゾール
1-(4-(ブロモメチル)フェニル)エタノン