BIBR-1532

BIBR-1532 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TOC2981	BIBR 1532	321674-73-1	10mg	￥76000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC2981	BIBR 1532	321674-73-1	50mg	￥312000	2024-03-01	購入

BIBR-1532 化学特性,用途語,生産方法

説明

BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC₅₀ = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells. Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.

生物活性

Selective telomerase inhibitor (IC 50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.

BIBR-1532 上流と下流の製品情報

原材料

準備製品

BIBR-1532 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29321	58
Chemia Biotechnology（Shanghai） Co., Ltd	+8613816753574	info@chemia-pharm.com	CHINA	311	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58

321674-73-1(BIBR-1532)キーワード:

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• 321674-73-1
• 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID
• BIBR 1532
• 2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoicacid
• 2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl]amino]benzoic acid
• (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid
• BIBR 1532, >=98%
• BIBR 1532;BIBR-1532
• CS-1061
• (E)-2-(3-phenylbut-2-enamido)benzoic acid
• Benzoic acid, 2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]-
• 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID USP/EP/BP
• Telomerase Inhibitor X
• 2-[3-(NAPHTHALEN-2-YL)BUT-2-ENAMIDO]BENZOIC ACID
• 2-[[(E)-3-(2-ナフチル)-2-ブテノイル]アミノ]安息香酸
• BIBR-1532
• 2-[(2E)-3-(ナフタレン-2-イル)ブタ-2-エンアミド]安息香酸