ChemicalBook
Chinese english Germany Korea

トリメチルアミン水溶液 3 0 %

トリメチルアミン水溶液 3 0 % 化学構造式
75-50-3
CAS番号.
75-50-3
化学名:
トリメチルアミン水溶液 3 0 %
别名:
トリメチルアミン (約25%メタノール溶液, 約3.2mol/L);トリメチルアミン (約28%水溶液, 約4.3mol/L);N,N-ジメチルメタンアミン;トリメチルアミン;N,N-ジメチルメチルアミン;トリメチルアミン,エタノール溶液;トリメチルアミン溶液;トリメチルアミン水溶液;トリメチルアミン (約13%テトラヒドロフラン溶液, 約2mol/L);トリメチルアミン (約25%イソプロピルアルコール溶液, 約3mol/L);トリメチルアミン (約25%エタノール溶液, 約3mol/L);トリメチルアミン (約13%アセトニトリル溶液, 約2mol/L);トリメチルアミン (約8%トルエン溶液, 約1mol/L);30% トリメチルアミン溶液;トリメチルアミン30%水溶液;トリメチルアミン(30%水溶液);30%トリメチルアミン溶液;トリメチルアミン 溶液;トリメチルアミン水溶液 3 0 %
英語化学名:
Trimethylamine
英語别名:
ai3-15639;FEMA 3241;TRIMETHYLAMIN;TRIMETHYLAMINE;Trimethylamide;femanumber:3241;TRIMETHYLAMINE HCL;TriMethylaMine dimethylmethaneamine;TRIMETHYLAMINE HYDRO
CBNumber:
CB6332996
化学式:
C3H9N
分子量:
59.11
MOL File:
75-50-3.mol

トリメチルアミン水溶液 3 0 % 物理性質

融点 :
283-284 °C (dec.)(lit.)
沸点 :
3-4 °C(lit.)
比重(密度) :
0.83-0.88 g/mL at 20 °C
蒸気密度:
2.09 (vs air)
蒸気圧:
430 mm Hg ( 25 °C)
屈折率 :
n20/D 1.357
FEMA :
3241 | TRIMETHYLAMINE
闪点 :
38 °F
貯蔵温度 :
2-8°C
溶解性:
very soluble in water, slightly soluble in alcohol, ether, benzene, toluene, xylene, ethylbenzene, chloroform maximum allowable concentration: TLV 10 p.p.m. (24 mg/m3) and STEL of 15 p.p.m. (36 mg/m3) (ACGIH 1986)
外見 :
Liquid
酸解離定数(Pka):
pKb (25°): 4.13
色:
Colorless
爆発限界(explosive limit):
11.6%
水溶解度 :
Soluble In Water, 8.9e+005 mg/L.
凝固点 :
-117.1℃
Sensitive :
Hygroscopic
Merck :
14,9710
JECFA Number:
1610
BRN :
956566
安定性::
Stable. Incompatible with a wide variety of materials, including bases, acids, oxidizing agents, brass, zinc, magnesium, aluminium, mercury, mercury oxides, acid chlorides, acid anhydrides. Hygroscopic. Highly flammable. Readily forms explosive mixtures with air.
CAS データベース:
75-50-3(CAS DataBase Reference)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  Xi,C,F+,Xn,F
Rフレーズ  36/37/38-34-20/22-12-41-37/38-20-11
Sフレーズ  26-36-45-36/37/39-16-29-39-3
RIDADR  UN 2924 3/PG 2
WGK Germany  1
RTECS 番号 YH2700000
3-10
自然発火温度 374 °F
TSCA  Yes
国連危険物分類  3
容器等級  II
HSコード  29211100
消防法 危-4-1-II
化審法 優先評価化学物質
安衛法 有機則 第二種有機溶剤等
PRTR法 第一種指定化学物質
毒劇物取締法 劇物
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H220 極めて可燃性/引火性の高いガス 可燃性/引火性ガス 1 危険 P210, P377, P381, P403
H224 極めて引火性の高い液体および蒸気 引火性液体 1 危険
H225 引火性の高い液体および蒸気 引火性液体 2 危険 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H280 加圧ガス;熱すると爆発のおそれ 高圧ガス 高圧ガス
液化ガス
溶解ガス
警告 P410+P403
H302 飲み込むと有害 急性毒性、経口 4 警告 P264, P270, P301+P312, P330, P501
H314 重篤な皮膚の薬傷?眼の損傷 皮膚腐食性/刺激性 1A, B, C 危険 P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 P264, P280, P302+P352, P321,P332+P313, P362
H318 重篤な眼の損傷 眼に対する重篤な損傷性/眼刺激 性 1 危険 P280, P305+P351+P338, P310
H332 吸入すると有害 急性毒性、吸入 4 警告 P261, P271, P304+P340, P312
H333 吸入すると有害のおそれ 急性毒性、吸入 5 P304+P312
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告
H351 発がんのおそれの疑い 発がん性 2 警告 P201, P202, P281, P308+P313, P405,P501
H402 水生生物に有害 水生環境有害性、急性毒性 3
H412 長期的影響により水生生物に有害 水生環境有害性、慢性毒性 3 P273, P501
注意書き
P210 熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
P260 粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P303+P361+P353 皮膚(または髪)に付着した場合:直ちに汚染された衣 類をすべて脱ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P310 ただちに医師に連絡すること。
P405 施錠して保管すること。
P410+P403 日光から遮断し、換気の良い場所で保管するこ と。

トリメチルアミン水溶液 3 0 % 価格 もっと(25)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01W0120-0284 30%トリメチルアミン溶液
30% Trimethylamine Solution
75-50-3 500mL ¥1900 2018-12-26 購入
東京化成工業 T0464 トリメチルアミン (約28%水溶液, 約4.3mol/L)
Trimethylamine (ca. 28% in Water, ca. 4.3mol/L)
75-50-3 25mL ¥1600 2018-12-04 購入
東京化成工業 T0464 トリメチルアミン (約28%水溶液, 約4.3mol/L)
Trimethylamine (ca. 28% in Water, ca. 4.3mol/L)
75-50-3 500mL ¥2300 2018-12-04 購入
関東化学株式会社(KANTO) 27044-1A トリメチルアミン,エタノール溶液
Trimethylamine, in ethanol
75-50-3 25mL ¥3200 2018-12-13 購入
関東化学株式会社(KANTO) 27044-2A トリメチルアミン,エタノール溶液
Trimethylamine, in ethanol
75-50-3 250mL ¥6400 2018-12-13 購入

トリメチルアミン水溶液 3 0 % 化学特性,用途語,生産方法

外観

無色澄明の液体

溶解性

水及びエタノールと任意の割合で混和する。

用途

塩化コリン原料、逆性石けん?イオン交換樹脂原料、医薬?農薬?カチオン活性剤原料

用途

有機合成原料。

用途

医薬農薬原料等

化学的特性

Colorless gas at room temperature; fishy ammoniacal odor; readily liquefied. Anhydrous form shipped as liquefied compressed gas. Soluble in water, alcohol, and ether.

化学的特性

Trimethylamine is compressed gas or liquid. Flammable gas. Shipped as a compressed gas, it may be present in an aqueous solution. It has a strong, fishy, ammoniacal odor. The Odor Threshold is 0.00011-0.87 ppm. Warning: The Odor Threshold range is so broad that odor alone should not be used as a warning of potentially hazardous exposures.

化学的特性

Trimethylamine has a pungent, fishy, ammoniacal odor at low concentration.

天然物の起源

TMA is widely distributed in the environment as a normal constituent of animal and plant tissue and as a result of its formation during the decay of organic matter in plants, animals, fish, sewage and animal waste (Graedel 1978; Hippe et al 1977; Oremland et al 1982). The amine is formed primarily as the result of microbial degradation of the plant and animal constituents betaine and choline and from bacterial reduction of trimethylamine oxide, a common constituent of aquatic organisms. It also occurs naturally in a variety of foodstuffs and in tobacco smoke and these are the most likely sources of human exposure (HSDB 1988).
Numerous strains of bacteria isolated from various sources have been found capable of growing on TMA (HSDB 1988). Degradation products formed under anaerobic conditions include dimethylamine, formaldehyde, formate and C02, while under aerobic conditions, TMA is converted to dimethylamine, ammonia and methane.

使用

Organic synthesis, especially of choline salts, warning agent for natural gas, manufacture of disinfectants, flotation agent, insect attractant, quaternary ammonium compounds, plastics.

製造方法

From paraformaldehyde and ammonium chloride; by the action of formaldehyde and formic acid on ammonia.

調製方法

Trimethylamine (TMA) is produced by several methods: from the reaction of ammonia and methanol; from paraformaldehyde and ammonium chloride; by the action of formaldehyde and formic acid on ammonia; and by the interaction of methanol and ammonia over a catalyst at high temperature (Hawley 1981; HSDB 1988). TMA is sold as an aqueous solution or as a liquefied gas (Windholz et al 1983) in which the aqueous solution is available as 25, 30, and 40% and anhydrous as 99% minimum. The impurities consist of ammonia at no more than 0.2% by weight of solution and formaldehyde at no more than 0.3% by wt. of solution (Rick 1985). U.S. production was estimated to be approximately 15,322 tons in 1984 (HSDB 1988).

定義

ChEBI: A tertiary amine that is ammonia in which each hydrogen atom is substituted by an methyl group.

Aroma threshold values

Detection: 0.3 to 0.8 ppb; recognition: 500 ppb

一般的な説明

A colorless gas with a fishlike odor at low concentrations changing to ammonia-like odor at higher concentrations. Shipped as a liquid under its own vapor pressure. Contact with the unconfined liquid can cause frostbite from evaporative cooling or chemical type burns. The gasis corrosive and dissolves in water to form flammable, corrosive solutions. Gas is an asphyxiate by the displacement of air. Produces toxic oxides of nitrogen during combustion. Prolonged exposure to heat can cause the containers to rupture violently and rocket. Long-term inhalation of low concentrations or short -term inhalation of high concentrations has adverse health effects.

空気と水の反応

Highly flammable and easily ignited. Water soluble.

反応プロフィール

TRIMETHYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Contamination of an ethylene oxide tank with trimethylamine caused an explosion [BCISC Quart. Safety Summ., 1966, 37, 44].

健康ハザード

VAPOR: POISONOUS IF INHALED. Irritating to eyes, nose, and throat. LIQUID: Will burn skin and eyes. Harmful if swallowed.

健康ハザード

Skin burns and eye irritation are produced upon contact with TMA (Beard and Noe 1981; Sittig 1985). Inhalation of vapors causes coughing and vomiting; higher concentrations produce difficult breathing and pulmonary edema. In one reported accident, the explosion of a glass ampule resulted in a blast of vapor striking the victim's eyes. Although no mechanical injuries were evident, the epithelium from the cornea was lost (Grant 1974). The epithelium healed promptly and the eye was entirely normal within 4-5 d.

火災危険

FLAMMABLE. Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area. Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back.

工業用途

TMA is used in the manufacturing of quaternary ammonium compounds, insect repellents, disinfectants, flotation agents, plastics, as a warning agent in gases, animal feed supplement, as a food additive for seafood flavor, and an ingredient in synthetic fermented egg protein product which is used to attract coyotes. In addition, it is used in organic synthesis of cationic emulsion polymers and as a chemical initiator for acetylcholine bromide [neuroregulator] (HSDB 1988; Anonymous 1981). The primary use (89%) is as a chemical intermediate for choline chloride (animal feed supplement), while 11% is used in other applications (HSDB 1988).

安全性プロファイル

Poison by intravenous route. Moderately toxic by subcutaneous and rectal routes. Mildly toxic by inhalation. A very dangerous fire hazard when exposed to heat or flame. Self-reactive. Moderately explosive in the form of vapor when exposed to heat or flame. Can react with oxidizing materials. To fight fire, stop flow of gas. Potentially explosive reaction with bromine + heat, ethylene oxide, triethynylaluminum. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.

職業ばく露

Trimethylamine is used as a chemical intermediate in organic synthesis of quaternary ammonium com pounds; as an insect attractant; as a warning agent in natural gas; flotation agent.

代謝

Aliphatic amines are well absorbed from the gut and respiratory tract (Beard and Noe 1981). However, TMA is a normal constituent of mammalian urine, complicating its pharmacokinetic analysis. TMA is partially metabolized to ammonia and subsequently to urea in mammals. It is converted in part to TMA oxide which is readily reduced back to TMA (Anon. 1972). TMA also is partially metabolized by N-demethylation to form formaldehyde (Parke 1968).
In an experiment using 4 male volunteers, over 95% of the administered TMA was excreted in the N-oxide form, confirming N-oxidation as the major route of metabolism in man (Al-Waiz et al 1987a). A condition known as trimethylaminuria (fish-odor syndrome) is likely to result from an inborn error in N-oxidation (Al-Waiz et al 1987b). Renal tubular transport and metabolism was investigated in chickens and TMA was found to be almost entirely metabolized in vivo to TMA oxide (Acara et al 1977).
In healthy humans, 2 mmol choline chloride, choline stearate, or lecithin administered orally markedly increased the urinary excretion of TMA, dimethylamine, and monomethylamine, with choline chloride having the greatest effect. Choline is known to be converted to TMA in mammals by gut microorganisms (HSDB 1988). When rats were treated with 1 mmol/kg of choline chloride or lecithin, urinary excretion of TMA was significantly increased while dimethylamine and monomethylamine excretion was not altered (Zeisel et al 1983).
TMA is reported to stimulate NADPH oxidation by an amount equivalent to the amount of TMA oxide formed (LaDu et al 1971).

輸送方法

UN1083 Trimethylamine, anhydrous, Hazard Class: 2.1; Labels: 2.1-Flammable gas. Cylinders must be transported in a secure upright position, in a wellventilated truck. Protect cylinder and labels from physical damage. The owner of the compressed gas cylinder is the only entity allowed by federal law (49CFR) to transport and refill them. It is a violation of transportation regulations to refill compressed gas cylinders without the express written permission of the owner. UN1297 Trimethylamine, aqueous solutions with not >50% trimethylamine by mass, Hazard Class: 3; Labels: 3-Flammable liquid, 8-Corrosive material.

純化方法

Dry triethylamine by passing the gas through a tower filled with solid KOH. Water and impurities containing labile hydrogen were removed by treatment with freshly sublimed, ground, P2O5. It has been refluxed with acetic anhydride, and then distilled through a tube packed with HgO and BaO. [Comyns J Chem Soc 1557 1955.] For more extensive purification, trimethylamine is converted to the hydrochloride, crystallised (see below), and regenerated by treating the hydrochloride with excess aqueous 50% KOH, the gas is passed through a CaSO4 column into a steel cylinder containing sodium ribbon. After 1-2 days, the cylinder is cooled to -78o and hydrogen and air are removed by pumping. [Day & Felsing J Am Chem Soc 72 1698 1950.] Me3N has been distlled from trap-to-trap and degassed by freeze-pump-thaw [Halpern et al. J Am Chem Soc 108 3907 1986]. It is commercially supplied in a pressure tin. [Beilstein 4 H 43, 4 I 322, 4 II 553, 4 III 99, 4 IV 134.]

不和合性

A medium strong base. Violent reaction with strong oxidizers (such as chlorine, bromine, fluorine), ethylene oxide; nitrosating agents, for example, nitrites, sodium nitrite, nitrous gases, nitrous acid) capable of releasing carcinogenic nitrosamines.); keep away from mercury, strong acids. Corrosive to many metals, for example, zinc, brass, aluminum, copper, tin, and their alloys.

廃棄物の処理

Return refillable compressed gas cylinders to supplier. Nonrefillable cylinders should be disposed of in accordance with local, state and federal regulations. Allow remaining gas to vent slowly into atmosphere in an unconfined area or exhaust hood. Refillabletype cylinders should be returned to original supplier with any valve caps and outlet plugs secured and valve protection caps in place.

トリメチルアミン水溶液 3 0 % 上流と下流の製品情報

原材料

準備製品


トリメチルアミン水溶液 3 0 % 生産企業

Global( 144)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21714 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 24986 65
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

75-50-3(トリメチルアミン水溶液 3 0 %)キーワード:


  • 75-50-3
  • Trimethylamine >=99.5%
  • Trimethylamine (ca. 13% in Acetonitrile, ca. 2mol/L)
  • Trimethylamine, 45% w/w aqueous solution
  • Trimethylamine water solution TMA Trimethylamine N,N-dimethyl-Methanamine
  • ai3-15639
  • dimethylmethaneamine
  • femanumber:3241
  • Methanamine, N,N-dimethyl-
  • Methanamine,N,N-dimethyl-
  • Methylamine, N,N-dimethyl-
  • n,n-dimethyl-methanamin
  • trimethylamine(solutions)
  • trimethylamine,anhydrous
  • trimethylamineanhydre
  • Trimethylaminesolution
  • trimethylaminesolutions
  • N, N-DIMETHYLMETHYLAMINE HCL
  • TRIMETHYLAMINE HCL
  • FEMA 3241
  • Trimethylamine water solution 33%
  • Trimethylamine anhydrate
  • Trimethylamine,water solution
  • TRIMETHYLAMIN
  • TRIMETHYLAMINE CYL. WITH 27 L (NET ~15 K G)
  • TRIMETHYLAMINE 25 WT. % SOLUTION IN &
  • TRIMETHYLAMINE SOLUTION, ~45% IN WATER
  • TRIMETHYLAMINE, 40 WT. % SOLUTION IN WATER
  • Trimethylamine1M solution in THFAcroSeal§3
  • Trimethylamine,pure,33 wt.% solution in ethanol
  • Trimethylamine,25 wt.% in methanol
  • トリメチルアミン (約25%メタノール溶液, 約3.2mol/L)
  • トリメチルアミン (約28%水溶液, 約4.3mol/L)
  • N,N-ジメチルメタンアミン
  • トリメチルアミン
  • N,N-ジメチルメチルアミン
  • トリメチルアミン,エタノール溶液
  • トリメチルアミン溶液
  • トリメチルアミン水溶液
  • トリメチルアミン (約13%テトラヒドロフラン溶液, 約2mol/L)
  • トリメチルアミン (約25%イソプロピルアルコール溶液, 約3mol/L)
  • トリメチルアミン (約25%エタノール溶液, 約3mol/L)
  • トリメチルアミン (約13%アセトニトリル溶液, 約2mol/L)
  • トリメチルアミン (約8%トルエン溶液, 約1mol/L)
  • 30% トリメチルアミン溶液
  • トリメチルアミン30%水溶液
  • トリメチルアミン(30%水溶液)
  • 30%トリメチルアミン溶液
  • トリメチルアミン 溶液
  • トリメチルアミン水溶液 3 0 %
Copyright 2017 © ChemicalBook. All rights reserved