モノクローナル抗ARP3抗体 マウス宿主抗体 化学特性,用途語,生産方法
使用
Anti-APOBEC3A antibody produced in rabbit has also been used in immunofluorescence staining.
一般的な説明
The gene APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A) is mapped to human chromosome 22q13.1. The protein has a catalytically active deaminase domain. It belongs to the APOBEC3 genes family.
Biochem/physiol Actions
APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A) is a cytidine deaminase. APOBEC3 proteins are mainly involved in intracellular antiviral defense responses, particularly against retroviruses. They are also involved in carcinogenesis by dC (deoxycytidine) deamination, thereby causing DNA mutations. APOBEC3A also exhibits mRNA-editing function. It is involved with guanine-to-alanine editing in transcripts of WT1 (wilms tumor 1). Deletion in APOBEC3A gene is associated with breast cancer predisposition. This happens due to increased stability of APOBEC3A mRNA.
モノクローナル抗ARP3抗体 マウス宿主抗体 上流と下流の製品情報
原材料
準備製品