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Dolutegravir 2-Desfluoro Impurity

1863916-88-4

CAS番号.: 1863916-88-4

化学名:

别名:

英語名:: Dolutegravir 2-Desfluoro Impurity

英語别名:: 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

CBNumber:: CB64796145

化学式:: C20H20FN3O5

分子量:: 401.39

MOL File:: 1863916-88-4.mol

物理性質

安全性情報

用途語

生産企業 33

Dolutegravir 2-Desfluoro Impurity 物理性質

沸点 :: 675.7±55.0 °C(Predicted)

比重(密度) :: 1.49±0.1 g/cm3(Predicted)

溶解性:: DMSO (Slightly), Methanol (Slightly, Heated)

外見 :: Solid

酸解離定数(Pka):: 4.50±1.00(Predicted)

色:: Off-White to Light Brown

安全性情報

Dolutegravir 2-Desfluoro Impurity 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

Dolutegravir 2-Desfluoro Impurity 化学特性,用途語,生産方法

使用

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity 上流と下流の製品情報

原材料

準備製品

Dolutegravir 2-Desfluoro Impurity 生産企業

Global( 33)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8613627253706	sale@hdimpurity.com	China	1743	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2580	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-52878169 15701683040	sales@bjcomparison.com	China	4687	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai CR Corporation Limited	4006653949	fred.wen@crcorporation.cn	China	10108	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1072	58
Nanjing zehe Pharmaceutical Technology Co., Ltd	17768115366	henry124604479@163.com	China	247	58

1863916-88-4()キーワード:

ドルテグラビルドルテグラビルナトリウム

1863916-88-4
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity
Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity G
Dolutegravir 2-Desfluoro Impurity
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity 47
Dolutegravir Impurity 50
4-Fluoro Dolutegravir
Dolutegravir 4-Fluoro Impurity